Title | Applications of elastin-like polypeptides in tissue engineering |
Publication Type | Review Article |
Authors | Nettles, DL, Chilkoti, A, Setton, LA |
Secondary Title | Advanced Drug Delivery Reviews |
Year of Publication | 2010 |
Volume | 62 |
Pagination | 1479 - 1485 |
Date Published | 12/2010 |
Abstract | Elastin-like polypeptides (ELPs) have found utility in tissue engineering applications, not only because they are biocompatible, biodegradable, and non-immunogenic, but also because their amino acid sequence and molecular weight can be precisely controlled at the genetic or synthetic level, affording exquisite control over final protein functionality. This review presents a basic overview of ELP properties and modifications that are relevant to tissue engineering, as well as a discussion of the application of ELPs to cartilage, intervertebral disc, vascular graft, liver, ocular, and cell sheet engineering. |
Issue | 15 |
Short Title | Advanced Drug Delivery Reviews |
Citation Key | 93 |
ISSN Number | 0169409X |
DOI | 10.1016/j.addr.2010.04.002 |
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