Applications of elastin-like polypeptides in tissue engineering

TitleApplications of elastin-like polypeptides in tissue engineering
Publication TypeReview Article
AuthorsNettles, DL, Chilkoti, A, Setton, LA
Secondary TitleAdvanced Drug Delivery Reviews
Year of Publication2010
Pagination1479 - 1485
Date Published12/2010

Elastin-like polypeptides (ELPs) have found utility in tissue engineering applications, not only because they are biocompatible, biodegradable, and non-immunogenic, but also because their amino acid sequence and molecular weight can be precisely controlled at the genetic or synthetic level, affording exquisite control over final protein functionality. This review presents a basic overview of ELP properties and modifications that are relevant to tissue engineering, as well as a discussion of the application of ELPs to cartilage, intervertebral disc, vascular graft, liver, ocular, and cell sheet engineering.

Short TitleAdvanced Drug Delivery Reviews
Citation Key93
ISSN Number0169409X
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