| Title | Dual agonist fusion proteins |
| Publication Type | Patent |
| Year of Publication | 2021 |
| Authors | Chilkoti, A, Gilroy, C |
| Patent Version Number | US20210309722A1 |
| International Patent Number | US20210309722A1 |
| International Patent Classification | A1 |
| Date Published | 10/08/2021 |
| Abstract | Disclosed herein are fusion proteins including an elastin-like peptide domain, a GLP-1 receptor agonist domain attached N to a N-terminal end of the ELP domain, and a FGF21 receptor agonist domain attached to the C-terminal end of the ELP domain. Also disclosed are methods of making the fusion proteins, compositions including a plurality of fusion proteins, and uses of the fusion proteins and compositions |