Fabrication of ssDNA/Oligo(ethylene glycol) Monolayers and Complex Nanostructures by an Irradiation-Promoted Exchange Reaction

TitleFabrication of ssDNA/Oligo(ethylene glycol) Monolayers and Complex Nanostructures by an Irradiation-Promoted Exchange Reaction
Publication TypeJournal Article
Year of Publication2012
AuthorsKhan, NM, Tjong, V, Chilkoti, A, Zharnikov, M
JournalAngewandte Chemie International Edition
Volume51
Issue41
Pagination10303 - 10306
Date Published10/2012
Abstract

Creative design: An approach to preparing mixed monolayers of thiolated single-stranded DNA (ssDNA) and oligo(ethylene glycol)s (OEG-AT) in a broad range of compositions as well as ssDNA/OEG-AT patterns of any required shape (see top figure) has been shown. A combination of this approach with surface-initiated enzymatic polymerization allows complex 3D DNA nanostructures to be sculpted with high spatial precision (bottom).

DOI10.1002/anie.201204245
Short TitleAngew. Chem. Int. Ed.
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