|Title||Programmable liquid, gel and biohybrid compartments and methods of use|
|Year of Publication||2020|
|Authors||Lopez, GP, Simon, JR, Carroll, NJ, Chilkoti, A|
|Patent Version Number||US20200276553A1|
|International Patent Number||US20200276553A1|
|International Patent Classification||B01J13/06|
Nano- to microscale liquid coacervate particles are provided. The liquid coacervate particles are produced by a process including stimulating a population of liquid droplets containing one or a mixture of components to induce a phase separation point of a first component, and maintaining stimulation at the phase separation point to form a coacervate domain of the first component within each of the droplets to form the liquid coacervate particles. The self-assembled nano, meso, micro and macro liquid coacervate particles and related coated substrates can have utility in drug delivery, bioanalytical systems, controlled cell culture, tissue engineering, biomanufacturing and drug discovery.