Publications

2016
N. C. Tang and Chilkoti, A. , Combinatorial codon scrambling enables scalable gene synthesis and amplification of repetitive proteins, Nature Materials, 2016.
J. F. Nawroth, McDaniel, J. R. , Chilkoti, A. , Jordan, R. , and Luxenhofer, R. , Maleimide-Functionalized Poly(2-Oxazoline)s and Their Conjugation to Elastin-Like Polypeptides, Macromolecular Bioscience, p. n/a - n/a, 2016.
J. Liu, Pang, Y. , Bhattacharyya, J. , Liu, W. , Weitzhandler, I. , Li, X. , and Chilkoti, A. , Developing Precisely Defined Drug-Loaded Nanoparticles by Ring-Opening Polymerization of a Paclitaxel Prodrug, Advanced Healthcare Materials, p. n/a–n/a, 2016.
2015
F. G. Quiroz and Chilkoti, A. , Sequence heuristics to encode phase behaviour in intrinsically disordered protein polymers, Nature Materials, 2015.
S. Roberts, Dzuricky, M. , and Chilkoti, A. , Elastin-like polypeptides as models of intrinsically disordered proteins, FEBS Letters, 2015.
J. Bhattacharyya, Bellucci, J. J. , Weitzhandler, I. , McDaniel, J. R. , Spasojevic, I. , Li, X. , Lin, C. - C. , Chi, J. - T. A. , and Chilkoti, A. , A paclitaxel-loaded recombinant polypeptide nanoparticle outperforms Abraxane in multiple murine cancer models, Nature Communications, vol. 6, p. 7939, 2015.
N. K. Li, Fuss, W. H. , Tang, L. , Gu, R. , Chilkoti, A. , Zauscher, S. , and Yingling, Y. G. , Prediction of solvent-induced morphological changes of polyelectrolyte diblock copolymer micelles, Soft Matter, 2015.
W. Han, MacEwan, S. , Chilkoti, A. , and Lopez, G. , Bio-Inspired Synthesis of Hybrid Silica Nanoparticles Templated from Elastin-like Polypeptide Micelles, Nanoscale, p. ASAP, 2015.
C. A. Gilroy, Luginbuhl, K. M. , and Chilkoti, A. , Controlled release of biologics for the treatment of type 2 diabetes, Journal of Controlled Release, 2015.
R. Abedini-Nassab, Joh, D. Y. , Triggiano, M. A. , Baker, C. , Chilkoti, A. , Murdoch, D. M. , and Yellen, B. B. , Magnetophoretic Conductors and Diodes in a 3D Magnetic Field, Advanced Functional Materials, p. n/a - n/a, 2015.
R. Mukerji, Schaal, J. , Li, X. , Bhattacharyya, J. , Asai, D. , Zalutsky, M. R. , Chilkoti, A. , and Liu, W. , Spatiotemporally Photoradiation-Controlled Intratumoral Depot for Combination of Brachytherapy and Photodynamic Therapy for Solid Tumor, Biomaterials, 2015.
Y. Qi and Chilkoti, A. , Protein–polymer conjugation—moving beyond PEGylation, Current Opinion in Chemical Biology, vol. 28, pp. 181 - 193, 2015.
S. Bhattacharjee, Liu, W. , Wang, W. - H. , Weitzhandler, I. , Li, X. , Qi, Y. , Liu, J. , Pang, Y. , Hunt, D. F. , and Chilkoti, A. , Site-Specific Zwitterionic Polymer Conjugates of a Protein Have Long Plasma Circulation, ChemBioChem, p. n/a - n/a, 2015.
J. J. Bellucci, Bhattacharyya, J. , and Chilkoti, A. , A Noncanonical Function of Sortase Enables Site-Specific Conjugation of Small Molecules to Lysine Residues in Proteins, Angewandte Chemie International Edition, vol. 54, no. 2, pp. 441-445, 2015.
E. M. Mastria, Chen, M. , McDaniel, J. R. , Li, X. , Hyun, J. , Dewhirst, M. W. , and Chilkoti, A. , Doxorubicin-conjugated polypeptide nanoparticles inhibit metastasis in two murine models of carcinoma, Journal of Controlled Release, 2015.
R. Abedini-Nassab, Joh, D. Y. , Van Heest, M. A. , Yi, J. S. , Baker, C. , Taherifard, Z. , Margolis, D. M. , Garcia, V. J. , Chilkoti, A. , Murdoch, D. M. , and Yellen, B. B. , Characterizing the Switching Thresholds of Magnetophoretic Transistors, Advanced Materials, p. n/a - n/a, 2015.
E. Garanger, MacEwan, S. R. , Sandre, O. , Brûlet, A. , Bataille, L. , Chilkoti, A. , and Lecommandoux, S. , Structural Evolution of a Stimulus-Responsive Diblock Polypeptide Micelle by Temperature Tunable Compaction of its Core, Macromolecules, p. 150909074852008, 2015.
W. Hassouneh, Zhulina, E. B. , Chilkoti, A. , and Rubinstein, M. , Elastin-like Polypeptide Diblock Copolymers Self-Assemble into Weak Micelles, Macromolecules, p. ASAP, 2015.
A. Ghoorchian, Simon, J. R. , Bharti, B. , Han, W. , Zhao, X. , Chilkoti, A. , and López, G. P. , Bioinspired Reversibly Cross-linked Hydrogels Comprising Polypeptide Micelles Exhibit Enhanced Mechanical Properties, Advanced Functional Materials, vol. 25, no. 21, pp. 3122 - 3130, 2015.
K. A. Kimmerline, Furman, B. D. , Mangiapani, D. S. , Moverman, M. A. , Sinclair, M. S. , Huebner, J. L. , Chilkoti, A. , Kraus, V. B. , Setton, L. A. , Guilak, F. , and Olson, S. A. , Sustained intra-articular delivery of IL-1Ra from a thermally-responsive elastin-like polypeptide as a therapy for post-traumatic arthritis, European Cells and Materials, vol. 29, pp. 124-140, 2015.
2014
S. R. MacEwan and Chilkoti, A. , Applications of elastin-like polypeptides in drug delivery, Journal of Controlled Release. 2014.
S. R. MacEwan, Hassouneh, W. , and Chilkoti, A. , Non-chromatographic Purification of Recombinant Elastin-like Polypeptides and their Fusions with Peptides and Proteins from Escherichia coli, Journal of Visualized Experiments, no. 88, p. e51583, 2014.
V. Tjong, Tang, L. , Zauscher, S. , and Chilkoti, A. , “Smart” DNA interfaces, Chemical Society Reviews, vol. 43, no. 5. p. 1612, 2014.
J. Liu, Liu, W. , Weitzhandler, I. , Bhattacharyya, J. , Li, X. , Wang, J. , Qi, Y. , Bhattacharjee, S. , and Chilkoti, A. , Ring-Opening Polymerization of Prodrugs: A Versatile Approach to Prepare Well-Defined Drug-Loaded Nanoparticles, Angewandte Chemie International Edition, p. ASAP, 2014.
J. R. McDaniel, Weitzhandler, I. , Prevost, S. , Vargo, K. B. , Appavou, M. - S. , Hammer, D. A. , Gradzielski, M. , and Chilkoti, A. , Noncanonical Self-Assembly of Highly Asymmetric Genetically Encoded Polypeptide Amphiphiles into Cylindrical Micelles, Nano Letters, vol. 14, no. 11, pp. 6590–6598, 2014.

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