Amphiphilic polynucleotides

TitleAmphiphilic polynucleotides
Publication TypePatent
Year of Publication2022
AuthorsChilkoti, A, Zauscher, S, Tang, L, Deshpande, S
International Patent Number11512314
Date PublishedNov-29-2022
AssigneeAshutosh Chilkoti
CountryUnited States
Patent TypeGrant
Patent Number11512314
Abstract

Compositions and methods disclosed herein can help provide improved delivery of non-natural therapeutic nucleotides for the treatment of diseases such as cancer. An example composition includes an assembly of amphiphilic polynucleotides, where each amphiphilic polynucleotide includes an aptamer portion, a first nucleotide portion, and a second nucleotide portion.