Dual agonist fusion proteins

TitleDual agonist fusion proteins
Publication TypePatent
Year of Publication2021
AuthorsChilkoti, A, Gilroy, C
Patent Version NumberUS20210309722A1
International Patent NumberUS20210309722A1
International Patent ClassificationA1
Date Published10/08/2021

Disclosed herein are fusion proteins including an elastin-like peptide domain, a GLP-1 receptor agonist domain attached N to a N-terminal end of the ELP domain, and a FGF21 receptor agonist domain attached to the C-terminal end of the ELP domain. Also disclosed are methods of making the fusion proteins, compositions including a plurality of fusion proteins, and uses of the fusion proteins and compositions