Long circulating genetically encoded intrinsically disordered zwitterionic polypeptides for drug delivery

TitleLong circulating genetically encoded intrinsically disordered zwitterionic polypeptides for drug delivery
Publication TypeJournal Article
Year of Publication2019
AuthorsBanskota, S, Yousefpour, P, Kirmani, N, Li, X, Chilkoti, A
JournalBiomaterials
Volume192
Start Page475
Pagination475-485
Date Published02/2019
Abstract

Zwitterionic polypeptides with high chemical specificity and “stealth”-like behavior have superior pharmacokinetics compared with uncharged polypeptides in mice.

URLhttps://www.sciencedirect.com/science/article/pii/S0142961218307890
DOI10.1016/j.biomaterials.2018.11.012