Chilkoti Group

The Chilkoti group carries out research in two areas: (1) Biomolecular Materials, with a focus on genetically encoded stimulus responsive peptide polymers and fusion proteins for application in protein purification and drug delivery; and (2) Biointerface Science, with a focus on protein-polymer conjugates, the development of low-cost, point-of-care clinical diagnostics, and plasmonic biosensors.

Recent Publications

S. Roberts, Miao, V. , Costa, S. , Simon, J. , Kelly, G. , Shah, T. , Zauscher, S. , and Chilkoti, A. , Complex microparticle architectures from stimuli-responsive intrinsically disordered proteins, Nature Communications, vol. 11174783508483331352973387927131122614231512763084692244114631423911057116575891673394629714181393017124333111641424, no. 136512, 2020.
S. Saha, Banskota, S. , Roberts, S. , Kirmani, N. , and Chilkoti, A. , Engineering the Architecture of Elastin‐Like Polypeptides: From Unimers to Hierarchical Self‐Assembly, Advanced Therapeutics, vol. 24181399872461, p. 1900164, 2020.
J. Wang, Saha, S. , Schaal, J. L. , Yousefpour, P. , Li, X. , and Chilkoti, A. , Heuristics for the Optimal Presentation of Bioactive Peptides on Polypeptide Micelles, Nano Letters, vol. 19, no. 11, pp. 7977 - 7987, 2019.

We are a Duke Green Lab