Chilkoti Group

The Chilkoti group carries out research in two areas: (1) Biomolecular Materials, with a focus on genetically encoded stimulus responsive peptide polymers and fusion proteins for application in protein purification and drug delivery; and (2) Biointerface Science, with a focus on protein-polymer conjugates, the development of low-cost, point-of-care clinical diagnostics, and plasmonic biosensors.

Recent Publications

M. Dzuricky, Roberts, S. , and Chilkoti, A. , Convergence of Artificial Protein Polymers and Intrinsically Disordered Proteins, Biochemistry, 2018.
N. K. Li, Roberts, S. , Quiroz, F. G. , Chilkoti, A. , and Yingling, Y. G. , Sequence directionality dramatically affects LCST behavior of elastin-like polypeptides, Biomacromolecules, 2018.
D. Mozhdehi, Luginbuhl, K. M. , Simon, J. R. , Dzuricky, M. , Berger, üdiger, H. Varol, S. , Huang, F. C. , Buehne, K. L. , Mayne, N. R. , Weitzhandler, I. , Bonn, M. , Parekh, S. H. , and Chilkoti, A. , Genetically encoded lipid–polypeptide hybrid biomaterials that exhibit temperature-triggered hierarchical self-assembly, Nature Chemistry, vol. 428, 2018.

We are a Duke Green Lab