Chilkoti Group
The Chilkoti group carries out research in two areas: (1) Biomolecular Materials, with a focus on genetically encoded stimulus responsive peptide polymers and fusion proteins for application in protein purification and drug delivery; and (2) Biointerface Science, with a focus on protein-polymer conjugates, the development of low-cost, point-of-care clinical diagnostics, and plasmonic biosensors.
Recent Publications
Ring-Opening Polymerization of Prodrugs: A Versatile Approach to Prepare Well-Defined Drug-Loaded Nanoparticles. Angewandte Chemie International Edition (2014): ASAP. Abstract
Plasmonic biosensors. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology (2014): ASAP. Abstract
A Noncanonical Function of Sortase Enables Site-Specific Conjugation of Small Molecules to Lysine Residues in Proteins. Angewandte Chemie International Edition (2014): ASAP. Abstract
Noncanonical Self-Assembly of Highly Asymmetric Genetically Encoded Polypeptide Amphiphiles into Cylindrical Micelles. Nano Letters. 14.11 (2014): 6590-6598. Abstract
Recent News
January 20, 2015:
Chilkoti Group members have been spotted taking in a recent Duke basketball game.
December 25, 2014:
Tosh is honored to have been named a fellow of the National Academy of Inventors! (see also the Pratt article)
December 20, 2014:
The Chilkoti Group brunching it up for the holidays:
