The Chilkoti group carries out research in two areas: (1) Biomolecular Materials, with a focus on genetically encoded stimulus responsive peptide polymers and fusion proteins for application in protein purification and drug delivery; and (2) Biointerface Science, with a focus on protein-polymer conjugates, the development of low-cost, point-of-care clinical diagnostics, and plasmonic biosensors.
“Active Targeting of Cancer Cells by Nanobody Decorated Polypeptide Micelle with Bio-orthogonally Conjugated Drug”, Nano Letters, 2018.,
“Long circulating genetically encoded intrinsically disordered zwitterionic polypeptides for drug delivery”, Biomaterials, vol. 192, pp. 475-485, 2019.,
“Nanoparticle formulation improves doxorubicin efficacy by enhancing host antitumor immunity”, Journal of Controlled Release, vol. 269, pp. 364-373, 2018.,