The Chilkoti group carries out research in two areas: (1) Biomolecular Materials, with a focus on genetically encoded stimulus responsive peptide polymers and fusion proteins for application in protein purification and drug delivery; and (2) Biointerface Science, with a focus on protein-polymer conjugates, the development of low-cost, point-of-care clinical diagnostics, and plasmonic biosensors.
“A brush-polymer/exendin-4 conjugate reduces blood glucose levels for up to five days and eliminates poly(ethylene glycol) antigenicity”, Nature Biomedical Engineering, vol. 1, p. 0002, 2016.,
“Magnetophoretic Transistors in a Tri-axial Magnetic Field”, Lab Chip, 2016.,
“A Modular Method for the High-Yield Synthesis of Site-Specific Protein-Polymer Therapeutics”, Angewandte Chemie International Edition, 2016.,