Chilkoti Group
The Chilkoti group carries out research in two areas: (1) Biomolecular Materials, with a focus on genetically encoded stimulus responsive peptide polymers and fusion proteins for application in protein purification and drug delivery; and (2) Biointerface Science, with a focus on protein-polymer conjugates, the development of low-cost, point-of-care clinical diagnostics, and plasmonic biosensors.
Recent Publications
Sustained intra-articular delivery of IL-1Ra from a thermally-responsive elastin-like polypeptide as a therapy for post-traumatic arthritis. European Cells and Materials. 29 (2015): 124-140. Abstract
Doxorubicin-conjugated polypeptide nanoparticles inhibit metastasis in two murine models of carcinoma. Journal of Controlled Release (2015). Abstract
Ring-Opening Polymerization of Prodrugs: A Versatile Approach to Prepare Well-Defined Drug-Loaded Nanoparticles. Angewandte Chemie International Edition (2014): ASAP. Abstract
Plasmonic biosensors. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 7.2 (2014): 152-168. Abstract
Recent News
January 20, 2015:
Chilkoti Group members have been spotted taking in a recent Duke basketball game.
December 25, 2014:
Tosh is honored to have been named a fellow of the National Academy of Inventors! (see also the Pratt article)
December 20, 2014:
The Chilkoti Group brunching it up for the holidays:
