Chilkoti Group

The Chilkoti group carries out research in two areas: (1) Biomolecular Materials, with a focus on genetically encoded stimulus responsive peptide polymers and fusion proteins for application in protein purification and drug delivery; and (2) Biointerface Science, with a focus on protein-polymer conjugates, the development of low-cost, point-of-care clinical diagnostics, and plasmonic biosensors.

Recent Publications

J. L. Schaal, Li, X. , Mastria, E. , Bhattacharyya, J. , Zalutsky, M. R. , Chilkoti, A. , and Liu, W. , Injectable polypeptide micelles that form radiation crosslinked hydrogels in situ for intratumoral radiotherapy, Journal of Controlled Release, vol. 228, pp. 58 - 66, 2016.
L. Li, Mo, C. - K. , Chilkoti, A. , López, G. P. , and Carroll, N. J. , Creating cellular patterns using genetically engineered, gold- and cell-binding polypeptides, Biointerphases, vol. 11, p. 021009, 2016.
J. Liu, Pang, Y. , Bhattacharyya, J. , Liu, W. , Weitzhandler, I. , Li, X. , and Chilkoti, A. , Developing Precisely Defined Drug-Loaded Nanoparticles by Ring-Opening Polymerization of a Paclitaxel Prodrug, Advanced Healthcare Materials, p. n/a–n/a, 2016.

We are a Duke Green Lab