The Chilkoti group carries out research in two areas: (1) Biomolecular Materials, with a focus on genetically encoded stimulus responsive peptide polymers and fusion proteins for application in protein purification and drug delivery; and (2) Biointerface Science, with a focus on protein-polymer conjugates, the development of low-cost, point-of-care clinical diagnostics, and plasmonic biosensors.
“Intratumoral delivery of brachytherapy and immunotherapy by a thermally triggered polypeptide depot”, Journal of Controlled Release, vol. 343, pp. 267-276, 2022.,
“Multiplexed, quantitative serological profiling of COVID-19 from blood by a point-of-care test”, Science Advances, vol. 7, no. 26, p. eabg4901, 2021.,
“Ultrasensitive point-of-care immunoassay for secreted glycoprotein detects Ebola infection earlier than PCR”, Science Translational Medicine, vol. 13, no. 588, p. eabd9696, 2021.,