The Chilkoti group carries out research in two areas: (1) Biomolecular Materials, with a focus on genetically encoded stimulus responsive peptide polymers and fusion proteins for application in protein purification and drug delivery; and (2) Biointerface Science, with a focus on protein-polymer conjugates, the development of low-cost, point-of-care clinical diagnostics, and plasmonic biosensors.
“Ultrasensitive point-of-care immunoassay for secreted glycoprotein detects Ebola infection earlier than PCR”, Science Translational Medicine, vol. 13, no. 588, p. eabd9696, 2021.,
“De novo engineering of intracellular condensates using artificial disordered proteins”, Nature Chemistry, 2020.,
“Complex microparticle architectures from stimuli-responsive intrinsically disordered proteins”, Nature Communications, vol. 11, no. 1342, 2020.,