The Chilkoti group carries out research in two areas: (1) Biomolecular Materials, with a focus on genetically encoded stimulus responsive peptide polymers and fusion proteins for application in protein purification and drug delivery; and (2) Biointerface Science, with a focus on protein-polymer conjugates, the development of low-cost, point-of-care clinical diagnostics, and plasmonic biosensors.
“Niclosamide-conjugated polypeptide nanoparticles inhibit Wnt signaling and colon cancer growth”, Nanoscale, 2017.,
“Inkjet-printed point-of-care immunoassay on a nanoscale polymer brush enables subpicomolar detection of analytes in blood”, Proceedings of the National Academy of Sciences, vol. 444121838814752313273035124695040711641683645298, p. 201703200, 2017.,
“One-week glucose control via zero-order release kinetics from an injectable depot of glucagon-like peptide-1 fused to a thermosensitive biopolymer”, Nature Biomedical Engineering, vol. 1261126223413166524147, p. 0078, 2017.,