Publications

2017

S. R. MacEwan, Weitzhandler, I. , Hoffmann, I. , Genzer, J. , Gradzielski, M. , and Chilkoti, A. , Phase behavior and self-assembly of perfectly sequence-defined and monodisperse multi-block copolypeptides, Biomacromolecules, 2017.
A. Weinberger, Walter, V. , MacEwan, S. R. , Schmatko, T. , Muller, P. , Schroder, éP. , Chilkoti, A. , and Marques, C. M. , Cargo self-assembly rescues affinity of cell-penetrating peptides to lipid membranes, Scientific Reports, vol. 7201158418994320183817121213014964232751123111781, p. 43963, 2017.
J. R. Simon, Carroll, N. J. , Rubinstein, M. , Chilkoti, A. , and ópez, G. P. , Programming molecular self-assembly of intrinsically disordered proteins containing sequences of low complexity, Nature Chemistry, 2017.
J. Bhattacharyya, Weitzhandler, I. , Ho, S. Bryan, McDaniel, J. R. , Li, X. , Tang, L. , Liu, J. , Dewhirst, M. , and Chilkoti, A. , Encapsulating a Hydrophilic Chemotherapeutic into Rod-Like Nanoparticles of a Genetically Encoded Asymmetric Triblock Polypeptide Improves Its Efficacy, Advanced Functional Materials, p. 1605421, 2017.
M. A. Gonzalez, Simon, J. R. , Ghoorchian, A. , Scholl, Z. , Lin, S. , Rubinstein, M. , Marszalek, P. , Chilkoti, A. , ópez, G. P. , and Zhao, X. , Strong, Tough, Stretchable, and Self-Adhesive Hydrogels from Intrinsically Unstructured Proteins, Advanced Materials, p. 1604743, 2017.
K. Widder, MacEwan, S. R. , Garanger, E. , úñez, V. , Lecommandoux, ébastien, Chilkoti, A. , and Hinderberger, D. , Characterisation of hydration and nanophase separation during the temperature response in hydrophobic/hydrophilic elastin-like polypeptide (ELP) diblock copolymers, Soft Matter, 2017.
D. Youngjin Joh, McGuire, F. , Abedini-Nassab, R. , Andrews, J. B. , Achar, R. K. , Zimmers, Z. , Mozhdehi, D. , Blair, R. , Albarghouthi, F. , Oles, W. , Richter, J. , Fontes, C. M. , Hucknall, A. M. , Yellen, B. B. , Franklin, A. D. , and Chilkoti, A. , Poly(oligo(ethylene glycol) methyl ether methacrylate) brushes on high-κ metal oxide dielectric surfaces for bioelectrical environments, ACS Applied Materials & Interfaces, 2017.

2016

K. W. H. Kwok, Dong, W. , Marinakos, S. M. , Liu, J. , Chilkoti, A. , Wiesner, M. R. , Chernick, M. , and Hinton, D. E. , Silver nanoparticle toxicity is related to coating materials and disruption of sodium concentration regulation, Nanotoxicology, pp. 1 - 12, 2016.
J. Wang, MacEwan, S. R. , and Chilkoti, A. , Quantitative Mapping of the Spatial Distribution of Nanoparticles in Endo-Lysosomes by Local pH, Nano Letters, 2016.
L. Li, Mo, C. - K. , Chilkoti, A. , López, G. P. , and Carroll, N. J. , Creating cellular patterns using genetically engineered, gold- and cell-binding polypeptides, Biointerphases, vol. 11, p. 021009, 2016.
S. Reagan MacEwan and Chilkoti, A. , From composition to cure: A systems engineering approach to anti-cancer drug carriers, Angewandte Chemie International Edition, 2016.
S. Banskota, Yousefpour, P. , and Chilkoti, A. , Cell-Based Biohybrid Drug Delivery Systems: The Best of the Synthetic and Natural Worlds, Macromolecular Bioscience, p. 1600361, 2016.
Y. Pang, Liu, J. , Qi, Y. , Li, X. , and Chilkoti, A. , A Modular Method for the High-Yield Synthesis of Site-Specific Protein-Polymer Therapeutics, Angewandte Chemie International Edition, 2016.
W. Liu, McDaniel, J. R. , Li, X. , Schaal, J. , Zalutsky, M. , and Chilkoti, A. , Development of an Injectable Brachytherapy Using Self-Assembly Polypeptides, Brachytherapy, vol. 15, p. S64, 2016.
J. L. Schaal, Li, X. , Mastria, E. , Bhattacharyya, J. , Zalutsky, M. R. , Chilkoti, A. , and Liu, W. , Injectable polypeptide micelles that form radiation crosslinked hydrogels in situ for intratumoral radiotherapy, Journal of Controlled Release, vol. 228, pp. 58 - 66, 2016.
R. Abedini-Nassab, Joh, D. , Albarghouthi, F. , Chilkoti, A. , Murdoch, D. Martin, and Yellen, B. , Magnetophoretic Transistors in a Tri-axial Magnetic Field, Lab Chip, 2016.
A. T. Pham, Seto, R. , önke, J. , Joh, D. Y. , Chilkoti, A. , Fried, E. , and Yellen, B. B. , Crystallization kinetics of binary colloidal monolayers, Soft Matter, 2016.
Y. Qi, Simakova, A. , Ganson, N. J. , Li, X. , Luginbuhl, K. M. , Ozer, I. , Liu, W. , Hershfield, M. S. , Matyjaszewski, K. , and Chilkoti, A. , A brush-polymer/exendin-4 conjugate reduces blood glucose levels for up to five days and eliminates poly(ethylene glycol) antigenicity, Nature Biomedical Engineering, vol. 1, p. 0002, 2016.
N. C. Tang and Chilkoti, A. , Combinatorial codon scrambling enables scalable gene synthesis and amplification of repetitive proteins, Nature Materials, 2016.
J. F. Nawroth, McDaniel, J. R. , Chilkoti, A. , Jordan, R. , and Luxenhofer, R. , Maleimide-Functionalized Poly(2-Oxazoline)s and Their Conjugation to Elastin-Like Polypeptides, Macromolecular Bioscience, p. n/a - n/a, 2016.
J. Liu, Pang, Y. , Bhattacharyya, J. , Liu, W. , Weitzhandler, I. , Li, X. , and Chilkoti, A. , Developing Precisely Defined Drug-Loaded Nanoparticles by Ring-Opening Polymerization of a Paclitaxel Prodrug, Advanced Healthcare Materials, p. n/a–n/a, 2016.

2015

F. G. Quiroz and Chilkoti, A. , Sequence heuristics to encode phase behaviour in intrinsically disordered protein polymers, Nature Materials, 2015.
S. Roberts, Dzuricky, M. , and Chilkoti, A. , Elastin-like polypeptides as models of intrinsically disordered proteins, FEBS Letters, 2015.
J. Bhattacharyya, Bellucci, J. J. , Weitzhandler, I. , McDaniel, J. R. , Spasojevic, I. , Li, X. , Lin, C. - C. , Chi, J. - T. A. , and Chilkoti, A. , A paclitaxel-loaded recombinant polypeptide nanoparticle outperforms Abraxane in multiple murine cancer models, Nature Communications, vol. 6, p. 7939, 2015.
W. Han, MacEwan, S. , Chilkoti, A. , and Lopez, G. , Bio-Inspired Synthesis of Hybrid Silica Nanoparticles Templated from Elastin-like Polypeptide Micelles, Nanoscale, p. ASAP, 2015.

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