Publications

2021
C. M. Fontes, Lipes, B. D. , Liu, J. , Agans, K. N. , Yan, A. , Shi, P. , Cruz, D. F. , Kelly, G. , Luginbuhl, K. M. , Joh, D. Y. , Foster, S. L. , Heggestad, J. , Hucknall, A. , Mikkelsen, M. H. , Pieper, C. F. , Horstmeyer, R. W. , Geisbert, T. W. , Gunn, M. D. , and Chilkoti, A. , Ultrasensitive point-of-care immunoassay for secreted glycoprotein detects Ebola infection earlier than PCR, Science Translational Medicine, vol. 13, no. 588, p. eabd9696, 2021.
D. Y. Joh, Heggestad, J. T. , Zhang, S. , Anderson, G. R. , Bhattacharyya, J. , Wardell, S. E. , Wall, S. A. , Cheng, A. B. , Albarghouthi, F. , Liu, J. , Oshima, S. , Hucknall, A. M. , Hyslop, T. , Hall, A. H. S. , Wood, K. C. , E. Hwang, S. , Strickland, K. C. , Wei, Q. , and Chilkoti, A. , Cellphone enabled point-of-care assessment of breast tumor cytology and molecular HER2 expression from fine-needle aspirates, npj Breast Cancer, vol. 7, no. 1, 2021.
J. T. Heggestad, Kinnamon, D. S. , Olson, L. B. , Liu, J. , Kelly, G. , Wall, S. A. , Oshabaheebwa, S. , Quinn, Z. , Fontes, C. M. , Joh, D. Y. , Hucknall, A. M. , Pieper, C. , Anderson, J. G. , Naqvi, I. A. , Chen, L. , Que, L. G. , Oguin, T. , Nair, S. K. , Sullenger, B. A. , Woods, C. W. , Burke, T. W. , Sempowski, G. D. , Kraft, B. D. , and Chilkoti, A. , Multiplexed, quantitative serological profiling of COVID-19 from blood by a point-of-care test, Science Advances, vol. 7, no. 26, p. eabg4901, 2021.
D. Mark Shapiro, Ney, M. , Eghtesadi, S. Ali, and Chilkoti, A. , Protein Phase Separation Arising from Intrinsic Disorder: First-Principles to Bespoke Applications, The Journal of Physical Chemistry B, vol. 125, no. 25, pp. 6740 - 6759, 2021.
I. C. Jenkins, Milligan, J. J. , and Chilkoti, A. , Genetically Encoded Elastin‐Like Polypeptides for Drug Delivery, Advanced Healthcare Materials, vol. 10, no. 13, p. 2100209, 2021.
K. M. Hainline, Shores, L. S. , Votaw, N. L. , Bernstein, Z. J. , Kelly, S. H. , Fries, C. N. , Madhira, M. S. , Gilroy, C. A. , Chilkoti, A. , and Collier, J. H. , Modular complement assemblies for mitigating inflammatory conditions, Proceedings of the National Academy of Sciences, vol. 118, no. 15, p. e2018627118, 2021.
K. Laaß, Quiroz, F. G. , Hunold, J. , Roberts, S. , Chilkoti, A. , and Hinderberger, D. , Nanoscopic Dynamics Dictate the Phase Separation Behavior of Intrinsically Disordered ProteinsNanoscopic Dynamics Dictate the Phase Separation Behavior of Intrinsically Disordered Proteins, Biomacromolecules, vol. 22, no. 2, pp. 1015 - 1025, 2021.
2020
M. Dzuricky, Rogers, B. A. , Shahid, A. , Cremer, P. S. , and Chilkoti, A. , De novo engineering of intracellular condensates using artificial disordered proteins, Nature Chemistry, 2020.
J. Wang, Min, J. , Eghtesadi, S. Ali, Kane, R. S. , and Chilkoti, A. , A Quantitative Study of the Interaction of Multivalent Ligand-Modified Nanoparticles with Breast Cancer Cells with Tunable Receptor Density, ACS Nano, 2020.
C. A. Gilroy, Capozzi, M. E. , Varanko, A. K. , Tong, J. , D'Alessio, D. A. , Campbell, J. E. , and Chilkoti, A. , Sustained release of a GLP-1 and FGF21 dual agonist from an injectable depot protects mice from obesity and hyperglycemia, Science Advances, vol. 6, no. 35, p. eaaz9890, 2020.
A. K. Varanko, Su, J. C. , and Chilkoti, A. , Elastin-Like Polypeptides for Biomedical Applications, Annual Review of Biomedical Engineering, vol. 22, no. 1, pp. 343 - 369, 2020.
S. Saha, Banskota, S. , Roberts, S. , Kirmani, N. , and Chilkoti, A. , Engineering the Architecture of Elastin‐Like Polypeptides: From Unimers to Hierarchical Self‐Assembly, Advanced Therapeutics, vol. 3, no. 3, 2020.
A. Varanko, Saha, S. , and Chilkoti, A. , Recent trends in protein and peptide-based biomaterials for advanced drug delivery., Adv Drug Deliv Rev, vol. 156, pp. 133-187, 2020.
J. T. Heggestad, Fontes, C. M. , Joh, D. Y. , Hucknall, A. M. , and Chilkoti, A. , In Pursuit of Zero 2.0: Recent Developments in Nonfouling Polymer Brushes for Immunoassays, Advanced Materials, vol. 32, no. 2, p. 1903285, 2020.
L. Li, C. Shields, W. , Huang, J. , Zhang, Y. , Ohiri, K. A. , Yellen, B. B. , Chilkoti, A. , and López, G. P. , Rapid capture of biomolecules from blood via stimuli-responsive elastomeric particles for acoustofluidic separation, The Analyst, vol. 145, no. 24, pp. 8087 - 8096, 2020.
S. Roberts, Miao, V. , Costa, S. , Simon, J. , Kelly, G. , Shah, T. , Zauscher, S. , and Chilkoti, A. , Complex microparticle architectures from stimuli-responsive intrinsically disordered proteins, Nature Communications, vol. 11, no. 1342, 2020.
2019
J. Wang, Saha, S. , Schaal, J. L. , Yousefpour, P. , Li, X. , and Chilkoti, A. , Heuristics for the Optimal Presentation of Bioactive Peptides on Polypeptide Micelles, Nano Letters, vol. 19, no. 11, pp. 7977 - 7987, 2019.
J. R. Simon, Eghtesadi, S. Ali, Dzuricky, M. , You, L. , and Chilkoti, A. , Engineered Ribonucleoprotein Granules Inhibit Translation in Protocells, Molecular Cell, 2019.
A. K. Varanko and Chilkoti, A. , Molecular and Materials Engineering for Delivery of Peptide Drugs to Treat Type 2 Diabetes, Advanced Healthcare Materials, no. 1801509, p. 1801509, 2019.
P. Yousefpour, Ahn, L. , Tewksbury, J. , Saha, S. , Costa, S. A. , Bellucci, J. J. , Li, X. , and Chilkoti, A. , Conjugate of Doxorubicin to Albumin‐Binding Peptide Outperforms Aldoxorubicin, Small, vol. 15, no. 12, p. 1804452, 2019.
D. Mozhdehi, Luginbuhl, K. M. , Dzuricky, M. , Costa, S. A. , Xiong, S. , Huang, F. C. , Lewis, M. M. , Zelenetz, S. R. , Colby, C. D. , and Chilkoti, A. , Genetically Encoded Cholesterol-Modified Polypeptides, Journal of the American Chemical Society, vol. 141, no. 2, pp. 945 - 951, 2019.
A. K. Varanko and Chilkoti, A. , Molecular and Materials Engineering for Delivery of Peptide Drugs to Treat Type 2 Diabetes., Adv Healthc Mater, vol. 8, no. 12, p. e1801509, 2019.
F. Garcia Quiroz, Li, N. K. , Roberts, S. , Weber, P. , Dzuricky, M. , Weitzhandler, I. , Yingling, Y. G. , and Chilkoti, A. , Intrinsically disordered proteins access a range of hysteretic phase separation behaviors, Science Advances, vol. 5, no. 10, p. eaax5177, 2019.
Z. Dai, Lee, A. J. , Roberts, S. , Sysoeva, T. A. , Huang, S. , Dzuricky, M. , Yang, X. , Zhang, X. , Liu, Z. , Chilkoti, A. , and You, L. , Versatile biomanufacturing through stimulus-responsive cell–material feedback, Nature Chemical Biology, vol. 15, 2019.
M. T. Manzari, Anderson, G. R. , Lin, K. H. , Soderquist, R. S. , Çakir, M. , Zhang, M. , Moore, C. E. , Skelton, R. N. , èvre, éva, Li, X. , Bellucci, J. J. , Wardell, S. E. , Costa, S. A. , Wood, K. C. , and Chilkoti, A. , Genomically informed small-molecule drugs overcome resistance to a sustained-release formulation of an engineered death receptor agonist in patient-derived tumor models, Science Advances, vol. 5, no. 9, p. eaaw9162, 2019.

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