Amphiphilic polynucleotides

TitleAmphiphilic polynucleotides
Publication TypePatent
Year of Publication2020
AuthorsChilkoti, A, Zauscher, S, Tang, L, Deshpande, S
Patent Version NumberUS20210009999A1
International Patent NumberUS20210009999A1
International Patent ClassificationC12N15/113
Application NumberUS20210009999A1
Date Published01/2021
Patent TypePatent Application

Compositions and methods disclosed herein can help provide improved delivery of non-natural therapeutic nucleotides for the treatment of diseases such as cancer. An example composition includes an assembly of amphiphilic polynucleotides, where each amphiphilic polynucleotide includes an aptamer portion, a first nucleotide portion, and a second nucleotide portion.