Amphiphilic polynucleotides

Publication Type
Patent
Patent Type
Patent Application
Patent Year
2020
Authors
A. Chilkoti; S. Zauscher; L. Tang; S. Deshpande
Patent Application Number
US20210009999A1
Abstract

Compositions and methods disclosed herein can help provide improved delivery of non-natural therapeutic nucleotides for the treatment of diseases such as cancer. An example composition includes an assembly of amphiphilic polynucleotides, where each amphiphilic polynucleotide includes an aptamer portion, a first nucleotide portion, and a second nucleotide portion.