Title | Peptide-based biopolymers in biomedicine and biotechnology |
Publication Type | Journal Article |
Year of Publication | 2008 |
Authors | Chow, DC, Nunalee, ML, Lim, DW, Simnick, AJ, Chilkoti, A |
Journal | Materials Science and Engineering: R: Reports |
Volume | 62 |
Issue | 4 |
Pagination | 125 - 155 |
Date Published | 9/2008 |
ISSN | 0927796X |
Abstract | Peptides are emerging as a new class of biomaterials due to their unique chemical, physical, and biological properties. The development of peptide-based biomaterials is driven by the convergence of protein engineering and macromolecular self-assembly. This review covers the basic principles, applications, and prospects of peptide-based biomaterials. We focus on both chemically synthesized and genetically encoded peptides, including poly-amino acids, elastin-like polypeptides, silk-like polymers, and other biopolymers based on repetitive peptide motifs. Applications of these engineered biomolecules in protein purification, controlled drug delivery, tissue engineering, and biosurface engineering are discussed. |
DOI | 10.1016/j.mser.2008.04.004 |
Short Title | Materials Science and Engineering: R: Reports |
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