Title | Tunable nonfouling surface of oligoethylene glycol |
Publication Type | Patent |
Year of Publication | 2021 |
Authors | Chilkoti, A, Ma, H |
Patent Version Number | US20210047520A1 |
International Patent Classification | C09D5/00 |
International Patent Number | US20210047520A1 |
Application Number | US20210047520A1 |
Date Published | 02/2021 |
Abstract | An article having a nonfouling surface thereon is comprises: (a) a substrate having a surface portion; (b) a linking layer on the surface portion; and (c) a polymer layer formed on the linking layer, preferably by the process of surface-initiated polymerization of monomeric units thereon, with each of the monomeric units comprising a monomer core group having at least one protein-resistant head group coupled thereto, to thereby form a brush molecule on the surface portion. The brush molecule comprising a stem formed from the polymerization of the monomer core groups, and a plurality of branches formed from the hydrophilic head group projecting from the stem. Methods of making and using such articles, are also described. |