Chilkoti Group

The Chilkoti group carries out research in two areas: (1) Biomolecular Materials, with a focus on genetically encoded stimulus responsive peptide polymers and fusion proteins for application in protein purification and drug delivery; and (2) Biointerface Science, with a focus on protein-polymer conjugates, the development of low-cost, point-of-care clinical diagnostics, and plasmonic biosensors.

Recent Publications

E. M. Mastria, Cai, L. Y. , Li, X. , Schaal, J. L. , and Chilkoti, A. , Nanoparticle formulation improves doxorubicin efficacy by enhancing host antitumor immunity, Journal of Controlled Release, vol. 269, pp. 364-373, 2018.
S. Roberts, Harmon, T. S. , Schaal, J. , Miao, V. , Li, K. , Hunt, A. , Wen, Y. , Oas, T. G. , Collier, J. H. , Pappu, R. V. , and Chilkoti, A. , Injectable tissue integrating networks from recombinant polypeptides with tunable order, Nature Materials, 2018.
C. M. Fontes, Achar, R. K. , Joh, D. Youngjin, Ozer, I. , Bhattacharjee, S. , Hucknall, A. , and Chilkoti, A. , Engineering the surface properties of a zwitterionic polymer brush to enable simple fabrication of inkjet printed point-of-care immunoassays, Langmuir, 2018.

We are a Duke Green Lab