Chilkoti Group

The Chilkoti group carries out research in two areas: (1) Biomolecular Materials, with a focus on genetically encoded stimulus responsive peptide polymers and fusion proteins for application in protein purification and drug delivery; and (2) Biointerface Science, with a focus on protein-polymer conjugates, the development of low-cost, point-of-care clinical diagnostics, and plasmonic biosensors.

Recent Publications

S. Roberts, Harmon, T. S. , Schaal, J. , Miao, V. , Li, K. , Hunt, A. , Wen, Y. , Oas, T. G. , Collier, J. H. , Pappu, R. V. , and Chilkoti, A. , Injectable tissue integrating networks from recombinant polypeptides with tunable order, Nature Materials, 2018.
C. M. Fontes, Achar, R. K. , Joh, D. Youngjin, Ozer, I. , Bhattacharjee, S. , Hucknall, A. , and Chilkoti, A. , Engineering the surface properties of a zwitterionic polymer brush to enable simple fabrication of inkjet printed point-of-care immunoassays, Langmuir, 2018.
R. Gu, Oweida, T. , Yingling, Y. G. , Chilkoti, A. , and Zauscher, S. , Enzymatic Synthesis of Nucleobase-Modified Single-Stranded DNA Offers Tunable Resistance to Nuclease Degradation, Biomacromolecules, 2018.

We are a Duke Green Lab