Chilkoti Group

The Chilkoti group carries out research in two areas: (1) Biomolecular Materials, with a focus on genetically encoded stimulus responsive peptide polymers and fusion proteins for application in protein purification and drug delivery; and (2) Biointerface Science, with a focus on protein-polymer conjugates, the development of low-cost, point-of-care clinical diagnostics, and plasmonic biosensors.

Recent Publications

A. Weinberger, Walter, V. , MacEwan, S. R. , Schmatko, T. , Muller, P. , Schroder, éP. , Chilkoti, A. , and Marques, C. M. , Cargo self-assembly rescues affinity of cell-penetrating peptides to lipid membranes, Scientific Reports, vol. 7201158418994320183817121213014964232751123111781, p. 43963, 2017.
J. R. Simon, Carroll, N. J. , Rubinstein, M. , Chilkoti, A. , and ópez, G. P. , Programming molecular self-assembly of intrinsically disordered proteins containing sequences of low complexity, Nature Chemistry, 2017.
M. A. Gonzalez, Simon, J. R. , Ghoorchian, A. , Scholl, Z. , Lin, S. , Rubinstein, M. , Marszalek, P. , Chilkoti, A. , ópez, G. P. , and Zhao, X. , Strong, Tough, Stretchable, and Self-Adhesive Hydrogels from Intrinsically Unstructured Proteins, Advanced Materials, p. 1604743, 2017.

We are a Duke Green Lab