Chilkoti Group

The Chilkoti group carries out research in two areas: (1) Biomolecular Materials, with a focus on genetically encoded stimulus responsive peptide polymers and fusion proteins for application in protein purification and drug delivery; and (2) Biointerface Science, with a focus on protein-polymer conjugates, the development of low-cost, point-of-care clinical diagnostics, and plasmonic biosensors.

Recent Publications

K. M. Luginbuhl, Schaal, J. L. , Umstead, B. , Mastria, E. M. , Li, X. , Banskota, S. , Arnold, S. , Feinglos, M. , Alessio, D. ’, and Chilkoti, A. , One-week glucose control via zero-order release kinetics from an injectable depot of glucagon-like peptide-1 fused to a thermosensitive biopolymer, Nature Biomedical Engineering, vol. 1261126223413166524147, p. 0078, 2017.
S. R. MacEwan and Chilkoti, A. , Von der Zusammensetzung zur Heilung: ein systemtechnischer Ansatz zur Entwicklung von Trägern für Tumortherapeutika, Angewandte Chemie, vol. 129, no. 24, pp. 6814 - 6837, 2017.
I. Weitzhandler, Dzuricky, M. , Hoffmann, I. , Quiroz, F. Garcia, Gradzielski, M. , and Chilkoti, A. , Micellar self-assembly of recombinant resilin-like/elastin-like block copolypeptides, Biomacromolecules, 2017.

We are a Duke Green Lab