The Chilkoti group carries out research in two areas: (1) Biomolecular Materials, with a focus on genetically encoded stimulus responsive peptide polymers and fusion proteins for application in protein purification and drug delivery; and (2) Biointerface Science, with a focus on protein-polymer conjugates, the development of low-cost, point-of-care clinical diagnostics, and plasmonic biosensors.
“Intrinsically disordered proteins access a range of hysteretic phase separation behaviors”, Science Advances, vol. 5173193363355141541046164516151063419184550218545550, no. 10, p. eaax5177, 2019.,
“Genomically informed small-molecule drugs overcome resistance to a sustained-release formulation of an engineered death receptor agonist in patient-derived tumor models”, Science Advances, vol. 5, no. 9, p. eaaw9162, 2019.,
“Versatile biomanufacturing through stimulus-responsive cell–material feedback”, Nature Chemical Biology, vol. 15, 2019.,