Felipe is a graduate from the Chilkoti Group whose PhD work uncovered a large and diverse family of "smart" peptide polymers, of which Elastin-like Polypeptides are a primitive relative. This work has significantly advanced our ability to create novel biomolecular materials that Felipe plans to explore for a number of biomedical applications.
Additional Information
EDUCATION
- Ph.D. in Biomedical Engineering 2008- April, 2013
Duke University
Dissertation: Syntax of Phase Transition Peptide Polymers with LCST and UCST Behavior
- M.S. in Biomedical Engineering 2008- 2011
Duke University
Thesis: “Smart” Behavior of Non‐Canonical Elastin‐Like Polypeptides
- B.S in Biomedical Engineering 2003– 2007
Escuela de Ingeniería de Antioquia and Universidad CES, Colombia.
PUBLICATIONS
PEER-REVIEWED JOURNAL ARTICLES
Link to Chilkoti Group Publications
W. Liu, J.R. McDaniel, X. Li, D. Asai, F. Garcia Quiroz, J. Schaal, J.S. Park, M. Zalutsky, A Chilkoti. Brachytherapy using injectable seeds that are self-assembled from genetically encoded polypeptides in situ. Cancer Research, 15:5956-5965, 2012.
D. Asai, D. Xu, W. Liu, F. Garcia Quiroz, D.J. Callahan, M.R. Zalutsky, S.L. Craig, A. Chilkoti. Protein polymer hydrogels by in situ, rapid and reversible self-gelation. Biomaterials, 33:5451-5458, 2012.
N. Higuita-Castro, D. Gallego-Perez, A. Pelaez-Vargas, F. García Quiroz, O.M. Posad, LE. López, C.A. Sarassa, P. Agudelo-Florez, F.J. Monteiro, A.S. Litsky, D.J. Hansford. Reinforced portland cement porous scaffolds for load- bearing bone tissue engineering applications. Journal of biomedical materials research. Part B, Applied biomaterials, 100B:501-507, 2012.
M. Amiram*, F. García Quiroz*, D. Callahan, A. Chilkoti. A Highly Parallel Method for Synthesizing DNA Repeats Enables the Discovery of ‘Smart’ Protein Polymers. Nature Materials, 10:141–148, 2011.
*Contributed equally to this work
D. Gallego, N. Higuita, F. García Quiroz, O.M. Posada, L.E. López, A.S. Litsky, D.J. Hansford. Portland cement for bone tissue engineering: effects of processing and metakaolin blends. Journal of biomedical materials research. Part B, Applied biomaterials, 98B: 305-315, 2011.
F. García Quiroz, O.M. Posada, D. Gallego, N. Higuita., P. Agudelo, C. Sarassa, D. Hansford, L.E. López. Housekeeping gene stability influences the quantification of osteogenic markers during stem cells differentiation to the osteogenic lineage. Cytotechnology, 62:109-120, 2010.
J.R. McDaniel, J.A. Mackay, F. García Quiroz, A. Chilkoti. Recursive Directional Ligation by Plasmid Reconstruction Allows Rapid and Seamless Cloning of Oligomeric Genes. Biomacromolecules, 11:944-952, 2010.
F. García Quiroz, SM Sinclair. Engineering antibody fragments: replicating the immune system and beyond. Revista Ingeniería Biomédica, 4:39-51, 2010.
R. Capone, F. Garcia Quiroz, P. Prangkio, I. Saluja, A.M. Sauer, M. R. Bautista, R.S. Turner, J. Yang, M. Mayer. Amyloid-β-induced ion flux in artificial lipid bilayers and neuronal cells: Resolving a controversy. Neurotoxicity Research, 16:1-13, 2009.
F. García Quiroz, O.M. Posada, D. Gallego, N. Higuita., P. Agudelo, C. Sarassa, D. Hansford, L.E. López. Isolation of human bone marrow mesenchymal stem cells and evaluation of their osteogenic potential. Revista Ingeniería Biomédica, 3: 48-55, 2008. [Cited in review article by Mosna et al. Stem Cells Dev, 2010]
D. Gallego, N. Higuita, F. García, N. Ferrell, D. Hansford. Bioactive coatings on Portland cement substrates: Surface precipitation of Apatite-like crystals. Materials Science and Engineering C, 28(3): 347-352, 2008.
MANUSCRIPTS IN PREPARATION
F. García Quiroz and A. Chilkoti. Syntax of “smart” peptide polymers governs their function. [Working draft available]
F. García Quiroz and A. Chilkoti. Key residue interactions govern the phase behavior of peptide polymers. [Working draft available]
PATENTS
A. Chilkoti*, F. García Quiroz*, M. Amiram. Phase transition biopolymers and methods of use. US Patent Application 20120121709, 2012. [Claims approved on March 2013]
*Contributed equally to this invention