Publications

2020

Varanko, Anastasia K., Jonathan C. Su, and Ashutosh Chilkoti. “Elastin-Like Polypeptides for Biomedical Applications.” Annual Review of Biomedical Engineering 22 (June 2020): 343–69. https://doi.org/10.1146/annurev-bioeng-092419-061127.

Banskota, Samagya, Soumen Saha, Jayanta Bhattacharya, Nadia Kirmani, Parisa Yousefpour, Michael Dzuricky, Nikita Zakharov, et al. “Genetically Encoded Stealth Nanoparticles of a Zwitterionic Polypeptide-Paclitaxel Conjugate Have a Wider Therapeutic Window than Abraxane in Multiple Tumor Models.” Nano Lett 20, no. 4 (April 8, 2020): 2396–2409. https://doi.org/10.1021/acs.nanolett.9b05094.

Roberts, Stefan, Vincent Miao, Simone Costa, Joseph Simon, Garrett Kelly, Tejank Shah, Stefan Zauscher, and Ashutosh Chilkoti. “Complex microparticle architectures from stimuli-responsive intrinsically disordered proteins.” Nature Communications 11, no. 1 (March 2020): 1342. https://doi.org/10.1038/s41467-020-15128-9.

Williams, Nicholas X., Nathan Watson, Daniel Y. Joh, Ashutosh Chilkoti, and Aaron D. Franklin. “Aerosol jet printing of biological inks by ultrasonic delivery.” Biofabrication 12, no. 2 (February 2020): 025004. https://doi.org/10.1088/1758-5090/ab5cf5.

Varanko, Anastasia, Soumen Saha, and Ashutosh Chilkoti. “Recent trends in protein and peptide-based biomaterials for advanced drug delivery.” Advanced Drug Delivery Reviews 156 (January 2020): 133–87. https://doi.org/10.1016/j.addr.2020.08.008.

Heggestad, Jacob T., Cassio M. Fontes, Daniel Y. Joh, Angus M. Hucknall, and Ashutosh Chilkoti. “In Pursuit of Zero 2.0: Recent Developments in Nonfouling Polymer Brushes for Immunoassays.” Advanced Materials (Deerfield Beach, Fla.) 32, no. 2 (January 2020): e1903285. https://doi.org/10.1002/adma.201903285.

Wang, Jing, Junseon Min, Seyed Ali Eghtesadi, Ravi S. Kane, and Ashutosh Chilkoti. “Quantitative Study of the Interaction of Multivalent Ligand-Modified Nanoparticles with Breast Cancer Cells with Tunable Receptor Density.” ACS Nano 14, no. 1 (January 2020): 372–83. https://doi.org/10.1021/acsnano.9b05689.

Lee, J. S., R. T. Hill, A. Chilkoti, and W. L. Murphy. “Surface Patterning.” In Biomaterials Science: An Introduction to Materials in Medicine, 553–73, 2020. https://doi.org/10.1016/B978-0-12-816137-1.00037-4.

2019

Wang, Jing, Soumen Saha, Jeffrey L. Schaal, Parisa Yousefpour, Xinghai Li, and Ashutosh Chilkoti. “Heuristics for the Optimal Presentation of Bioactive Peptides on Polypeptide Micelles.” Nano Letters 19, no. 11 (November 2019): 7977–87. https://doi.org/10.1021/acs.nanolett.9b03141.

Garcia Quiroz, Felipe, Nan K. Li, Stefan Roberts, Patrick Weber, Michael Dzuricky, Isaac Weitzhandler, Yaroslava G. Yingling, and Ashutosh Chilkoti. “Intrinsically disordered proteins access a range of hysteretic phase separation behaviors.” Science Advances 5, no. 10 (October 2019): eaax5177. https://doi.org/10.1126/sciadv.aax5177.

Dai, Zhuojun, Anna J. Lee, Stefan Roberts, Tatyana A. Sysoeva, Shuqiang Huang, Michael Dzuricky, Xiaoyu Yang, et al. “Versatile biomanufacturing through stimulus-responsive cell-material feedback.” Nature Chemical Biology 15, no. 10 (October 2019): 1017–24. https://doi.org/10.1038/s41589-019-0357-8.

Willems, Lione, Larissa van Westerveld, Stefan Roberts, Isaac Weitzhandler, Carlos Calcines Cruz, Armando Hernandez-Garcia, Ashutosh Chilkoti, Enrico Mastrobattista, John van der Oost, and Renko de Vries. “Nature of Amorphous Hydrophilic Block Affects Self-Assembly of an Artificial Viral Coat Polypeptide.” Biomacromolecules 20, no. 10 (October 2019): 3641–47. https://doi.org/10.1021/acs.biomac.9b00512.

Manzari, Mandana T., Gray R. Anderson, Kevin H. Lin, Ryan S. Soderquist, Merve Çakir, Mitchell Zhang, Chandler E. Moore, et al. “Genomically informed small-molecule drugs overcome resistance to a sustained-release formulation of an engineered death receptor agonist in patient-derived tumor models.” Sci Adv 5, no. 9 (September 2019): eaaw9162. https://doi.org/10.1126/sciadv.aaw9162.

Dzuricky, Michael, Sinan Xiong, Patrick Weber, and Ashutosh Chilkoti. “Avidity and Cell Uptake of Integrin-Targeting Polypeptide Micelles is Strongly Shape-Dependent.” Nano Letters 19, no. 9 (September 2019): 6124–32. https://doi.org/10.1021/acs.nanolett.9b02095.

Simon, Joseph R., Seyed Ali Eghtesadi, Michael Dzuricky, Lingchong You, and Ashutosh Chilkoti. “Engineered Ribonucleoprotein Granules Inhibit Translation in Protocells.” Molecular Cell 75, no. 1 (July 2019): 66-75.e5. https://doi.org/10.1016/j.molcel.2019.05.010.

Varanko, Anastasia K., and Ashutosh Chilkoti. “Molecular and Materials Engineering for Delivery of Peptide Drugs to Treat Type 2 Diabetes.” Advanced Healthcare Materials 8, no. 12 (June 2019): e1801509. https://doi.org/10.1002/adhm.201801509.

Willems, Lione, Stefan Roberts, Isaac Weitzhandler, Ashutosh Chilkoti, Enrico Mastrobattista, John van der Oost, and Renko de Vries. “Inducible Fibril Formation of Silk-Elastin Diblocks.” ACS Omega 4, no. 5 (May 2019): 9135–43. https://doi.org/10.1021/acsomega.9b01025.

Joh, Daniel Y., Zackary Zimmers, Manav Avlani, Jacob T. Heggestad, Hakan B. Aydin, Nancy Ganson, Shourya Kumar, et al. “Architectural Modification of Conformal PEG-Bottlebrush Coatings Minimizes Anti-PEG Antigenicity While Preserving Stealth Properties.” Adv Healthc Mater 8, no. 8 (April 2019): e1801177. https://doi.org/10.1002/adhm.201801177.

Koc, Julian, Tomer Simovich, Eric Schönemann, Ashutosh Chilkoti, Harrison Gardner, Geoffrey W. Swain, Kelli Hunsucker, André Laschewsky, and Axel Rosenhahn. “Sediment challenge to promising ultra-low fouling hydrophilic surfaces in the marine environment.” Biofouling 35, no. 4 (April 2019): 454–62. https://doi.org/10.1080/08927014.2019.1611790.

Yousefpour, Parisa, Lucie Ahn, Joel Tewksbury, Soumen Saha, Simone A. Costa, Joseph J. Bellucci, Xinghai Li, and Ashutosh Chilkoti. “Conjugate of Doxorubicin to Albumin-Binding Peptide Outperforms Aldoxorubicin.” Small (Weinheim an Der Bergstrasse, Germany) 15, no. 12 (March 2019): e1804452. https://doi.org/10.1002/smll.201804452.

Fontes, Cassio M., Rohan K. Achar, Daniel Y. Joh, Imran Ozer, Somnath Bhattacharjee, Angus Hucknall, and Ashutosh Chilkoti. “Engineering the Surface Properties of a Zwitterionic Polymer Brush to Enable the Simple Fabrication of Inkjet-Printed Point-of-Care Immunoassays.” Langmuir : The ACS Journal of Surfaces and Colloids 35, no. 5 (February 2019): 1379–90. https://doi.org/10.1021/acs.langmuir.8b01597.

Banskota, Samagya, Parisa Yousefpour, Nadia Kirmani, Xinghai Li, and Ashutosh Chilkoti. “Long circulating genetically encoded intrinsically disordered zwitterionic polypeptides for drug delivery.” Biomaterials 192 (February 2019): 475–85. https://doi.org/10.1016/j.biomaterials.2018.11.012.

Deshpande, Sonal, Yunqi Yang, Ashutosh Chilkoti, and Stefan Zauscher. “Enzymatic synthesis and modification of high molecular weight DNA using terminal deoxynucleotidyl transferase.,” 627:163–88, 2019. https://doi.org/10.1016/bs.mie.2019.07.044.

Costa, Simone A., Davoud Mozhdehi, Michael J. Dzuricky, Farren J. Isaacs, Eric M. Brustad, and Ashutosh Chilkoti. “Active Targeting of Cancer Cells by Nanobody Decorated Polypeptide Micelle with Bio-orthogonally Conjugated Drug.” Nano Letters 19, no. 1 (January 2019): 247–54. https://doi.org/10.1021/acs.nanolett.8b03837.

Mozhdehi, Davoud, Kelli M. Luginbuhl, Michael Dzuricky, Simone A. Costa, Sinan Xiong, Fred C. Huang, Mae M. Lewis, Stephanie R. Zelenetz, Christian D. Colby, and Ashutosh Chilkoti. “Genetically Encoded Cholesterol-Modified Polypeptides.” Journal of the American Chemical Society 141, no. 2 (January 2019): 945–51. https://doi.org/10.1021/jacs.8b10687.