Publications

2019

Z. Dai, Lee, A. J. , Roberts, S. , Sysoeva, T. A. , Huang, S. , Dzuricky, M. , Yang, X. , Zhang, X. , Liu, Z. , Chilkoti, A. , and You, L. , “Versatile biomanufacturing through stimulus-responsive cell–material feedback”, Nature Chemical Biology, vol. 15, 2019.

F. Garcia Quiroz, Li, N. K. , Roberts, S. , Weber, P. , Dzuricky, M. , Weitzhandler, I. , Yingling, Y. G. , and Chilkoti, A. , “Intrinsically disordered proteins access a range of hysteretic phase separation behaviors”, Science Advances, vol. 5, no. 10, p. eaax5177, 2019.

M. T. Manzari, Anderson, G. R. , Lin, K. H. , Soderquist, R. S. , Çakir, M. , Zhang, M. , Moore, C. E. , Skelton, R. N. , èvre, éva, Li, X. , Bellucci, J. J. , Wardell, S. E. , Costa, S. A. , Wood, K. C. , and Chilkoti, A. , “Genomically informed small-molecule drugs overcome resistance to a sustained-release formulation of an engineered death receptor agonist in patient-derived tumor models”, Science Advances, vol. 5, no. 9, p. eaaw9162, 2019.

D. Y. Joh, Zimmers, Z. , Avlani, M. , Heggestad, J. T. , Aydin, H. B. , Ganson, N. , Kumar, S. , Fontes, C. M. , Achar, R. K. , Hershfield, M. S. , Hucknall, A. M. , and Chilkoti, A. , “Architectural Modification of Conformal PEG‐Bottlebrush Coatings Minimizes Anti‐PEG Antigenicity While Preserving Stealth Properties”, Advanced Healthcare Materials, vol. 1801177, p. 1801177, 2019.

S. Banskota, Yousefpour, P. , Kirmani, N. , Li, X. , and Chilkoti, A. , “Long circulating genetically encoded intrinsically disordered zwitterionic polypeptides for drug delivery”, Biomaterials, vol. 192, pp. 475-485, 2019.

2018

M. Dzuricky, Roberts, S. , and Chilkoti, A. , “Convergence of Artificial Protein Polymers and Intrinsically Disordered Proteins”, Biochemistry, 2018.

N. K. Li, Roberts, S. , Quiroz, F. G. , Chilkoti, A. , and Yingling, Y. G. , “Sequence directionality dramatically affects LCST behavior of elastin-like polypeptides”, Biomacromolecules, 2018.

S. Roberts, Harmon, T. S. , Schaal, J. , Miao, V. , Li, K. , Hunt, A. , Wen, Y. , Oas, T. G. , Collier, J. H. , Pappu, R. V. , and Chilkoti, A. , “Injectable tissue integrating networks from recombinant polypeptides with tunable order”, Nature Materials, 2018.

R. Gu, Oweida, T. , Yingling, Y. G. , Chilkoti, A. , and Zauscher, S. , “Enzymatic Synthesis of Nucleobase-Modified Single-Stranded DNA Offers Tunable Resistance to Nuclease Degradation”, Biomacromolecules, 2018.

C. M. Fontes, Achar, R. K. , Joh, D. Youngjin, Ozer, I. , Bhattacharjee, S. , Hucknall, A. , and Chilkoti, A. , “Engineering the surface properties of a zwitterionic polymer brush to enable simple fabrication of inkjet printed point-of-care immunoassays”, Langmuir, 2018.

D. Mozhdehi, Luginbuhl, K. M. , Simon, J. R. , Dzuricky, M. , Berger, üdiger, H. Varol, S. , Huang, F. C. , Buehne, K. L. , Mayne, N. R. , Weitzhandler, I. , Bonn, M. , Parekh, S. H. , and Chilkoti, A. , “Genetically encoded lipid–polypeptide hybrid biomaterials that exhibit temperature-triggered hierarchical self-assembly”, Nature Chemistry, vol. 428, 2018.

C. A. Gilroy, Roberts, S. , and Chilkoti, A. , “Fusion of fibroblast growth factor 21 to a thermally responsive biopolymer forms an injectable depot with sustained anti-diabetic action”, Journal of Controlled Release, 2018.

S. A. Costa, Mozhdehi, D. , Dzuricky, M. J. , Isaacs, F. J. , Brustad, E. M. , and Chilkoti, A. , “Active Targeting of Cancer Cells by Nanobody Decorated Polypeptide Micelle with Bio-orthogonally Conjugated Drug”, Nano Letters, 2018.

P. Yousefpour, McDaniel, J. R. , Prasad, V. , Ahn, L. , Li, X. , Subrahmanyan, R. , Weitzhandler, I. , Suter, S. , and Chilkoti, A. , “Genetically Encoding Albumin Binding into Chemotherapeutic-loaded Polypeptide Nanoparticles Enhances Their Antitumor Efficacy”, Nano Letters, vol. 18, no. 12, pp. 7784 - 7793, 2018.

K. M. Ruff, Roberts, S. , Chilkoti, A. , and Pappu, R. V. , “Advances in Understanding Stimulus Responsive Phase Behavior of Intrinsically Disordered Protein Polymers”, Journal of Molecular Biology, 2018.

E. M. Mastria, Cai, L. Y. , Li, X. , Schaal, J. L. , and Chilkoti, A. , “Nanoparticle formulation improves doxorubicin efficacy by enhancing host antitumor immunity”, Journal of Controlled Release, vol. 269, pp. 364-373, 2018.

D. Mozhdehi, Luginbuhl, K. M. , Roberts, S. , and Chilkoti, A. , “Design of Sequence-Specific Polymers by Genetic Engineering”, in Sequence-Controlled Polymers, Wiley‐VCH Verlag GmbH & Co. KGaA, 2018, pp. 91-115.

2017

S. A. Costa, Simon, J. R. , Amiram, M. , Tang, L. , Zauscher, S. , Brustad, E. M. , Isaacs, F. J. , and Chilkoti, A. , “Photo-Crosslinkable Unnatural Amino Acids Enable Facile Synthesis of Thermoresponsive Nano- to Microgels of Intrinsically Disordered Polypeptides”, Advanced Materials, vol. 1521-4095, p. 1704878, 2017.

J. Wang, Dzuricky, M. , and Chilkoti, A. , “The Weak Link: Optimization of the Ligand–Nanoparticle Interface To Enhance Cancer Cell Targeting by Polymer Micelles”, Nano Letters, 2017.

K. M. Luginbuhl, Schaal, J. L. , Umstead, B. , Mastria, E. M. , Li, X. , Banskota, S. , Arnold, S. , Feinglos, M. , Alessio, D. ’, and Chilkoti, A. , “One-week glucose control via zero-order release kinetics from an injectable depot of glucagon-like peptide-1 fused to a thermosensitive biopolymer”, Nature Biomedical Engineering, vol. 1261126223413166524147, p. 0078, 2017.

S. R. MacEwan, Weitzhandler, I. , Hoffmann, I. , Genzer, J. , Gradzielski, M. , and Chilkoti, A. , “Phase behavior and self-assembly of perfectly sequence-defined and monodisperse multi-block copolypeptides”, Biomacromolecules, 2017.

K. M. Luginbuhl, Mozhdehi, D. , Dzuricky, M. , Yousefpour, P. , Huang, F. C. , Mayne, N. R. , Buehne, K. , and Chilkoti, A. , “Recombinant synthesis of hybrid lipid-peptide polymer fusions that self-assemble and encapsulate hydrophobic drugs”, Angewandte Chemie International Edition, 2017.

L. Tang, Navarro, L. A. , Chilkoti, A. , and Zauscher, S. , “High-Molecular-Weight Polynucleotides by Transferase-Catalyzed Living Chain-Growth Polycondensation”, Angewandte Chemie, vol. 129, no. 24, pp. 6882 - 6886, 2017.

S. R. MacEwan and Chilkoti, A. , “Von der Zusammensetzung zur Heilung: ein systemtechnischer Ansatz zur Entwicklung von Trägern für Tumortherapeutika”, Angewandte Chemie, vol. 129, no. 24, pp. 6814 - 6837, 2017.

J. R. Simon, Carroll, N. J. , Rubinstein, M. , Chilkoti, A. , and ópez, G. P. , “Programming molecular self-assembly of intrinsically disordered proteins containing sequences of low complexity”, Nature Chemistry, 2017.

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