Publications

Joh, Daniel Y., Jacob T. Heggestad, Shengwei Zhang, Gray R. Anderson, Jayanta Bhattacharyya, Suzanne E. Wardell, Simone A. Wall, et al. “Author Correction: Cellphone enabled point-of-care assessment of breast tumor cytology and molecular HER2 expression from fine-needle aspirates.” NPJ Breast Cancer 7, no. 1 (September 17, 2021): 126. https://doi.org/10.1038/s41523-021-00335-4.

Navarro, Luis A., Justin J. Ryan, Michael Dzuricky, Michael Gradzielski, Ashutosh Chilkoti, and Stefan Zauscher. “Microphase Separation of Resilin-like and Elastin-like Diblock Copolypeptides in Concentrated Solutions.” Biomacromolecules 22, no. 9 (September 2021): 3827–38. https://doi.org/10.1021/acs.biomac.1c00672.

Joh, Daniel Y., Jacob T. Heggestad, Shengwei Zhang, Gray R. Anderson, Jayanta Bhattacharyya, Suzanne E. Wardell, Simone A. Wall, et al. “Cellphone enabled point-of-care assessment of breast tumor cytology and molecular HER2 expression from fine-needle aspirates.” NPJ Breast Cancer 7, no. 1 (July 2, 2021): 85. https://doi.org/10.1038/s41523-021-00290-0.

Jenkins, Irene C., Joshua J. Milligan, and Ashutosh Chilkoti. “Genetically Encoded Elastin-Like Polypeptides for Drug Delivery.” Advanced Healthcare Materials 10, no. 13 (July 2021): e2100209. https://doi.org/10.1002/adhm.202100209.

Shapiro, Daniel Mark, Max Ney, Seyed Ali Eghtesadi, and Ashutosh Chilkoti. “Protein Phase Separation Arising from Intrinsic Disorder: First-Principles to Bespoke Applications.” The Journal of Physical Chemistry. B 125, no. 25 (July 2021): 6740–59. https://doi.org/10.1021/acs.jpcb.1c01146.

Heggestad, Jacob T., David S. Kinnamon, Lyra B. Olson, Jason Liu, Garrett Kelly, Simone A. Wall, Solomon Oshabaheebwa, et al. “Multiplexed, quantitative serological profiling of COVID-19 from blood by a point-of-care test.” Sci Adv 7, no. 26 (June 2021). https://doi.org/10.1126/sciadv.abg4901.

Fontes, Cassio M., Barbara D. Lipes, Jason Liu, Krystle N. Agans, Aiwei Yan, Patricia Shi, Daniela F. Cruz, et al. “Ultrasensitive point-of-care immunoassay for secreted glycoprotein detects Ebola infection earlier than PCR.” Sci Transl Med 13, no. 588 (April 7, 2021). https://doi.org/10.1126/scitranslmed.abd9696.

Hainline, Kelly M., Lucas S. Shores, Nicole L. Votaw, Zachary J. Bernstein, Sean H. Kelly, Chelsea N. Fries, Marisha S. Madhira, Caslin A. Gilroy, Ashutosh Chilkoti, and Joel H. Collier. “Modular complement assemblies for mitigating inflammatory conditions.” Proceedings of the National Academy of Sciences of the United States of America 118, no. 15 (April 2021): e2018627118. https://doi.org/10.1073/pnas.2018627118.

Laaß, Katharina, Felipe García Quiroz, Johannes Hunold, Stefan Roberts, Ashutosh Chilkoti, and Dariush Hinderberger. “Nanoscopic Dynamics Dictate the Phase Separation Behavior of Intrinsically Disordered Proteins.” Biomacromolecules 22, no. 2 (February 2021): 1015–25. https://doi.org/10.1021/acs.biomac.0c01768.

Zeng, Xiangze, Chengwen Liu, Martin J. Fossat, Pengyu Ren, Ashutosh Chilkoti, and Rohit V. Pappu. “Design of intrinsically disordered proteins that undergo phase transitions with lower critical solution temperatures.” APL Materials 9, no. 2 (February 2021): 021119. https://doi.org/10.1063/5.0037438.

Li, Linying, C Wyatt Shields, Jin Huang, Yiqun Zhang, Korine A. Ohiri, Benjamin B. Yellen, Ashutosh Chilkoti, and Gabriel P. López. “Rapid capture of biomolecules from blood via stimuli-responsive elastomeric particles for acoustofluidic separation.” The Analyst 145, no. 24 (January 2021): 8087–96. https://doi.org/10.1039/d0an01164a.

Yousefpour, P., A. Varanko, R. Subrahmanyan, and A. Chilkoti. “Recombinant Fusion of Glucagon-Like Peptide-1 and an Albumin Binding Domain Provides Glycemic Control for a Week in Diabetic Mice.” Advanced Therapeutics 3, no. 10 (October 1, 2020). https://doi.org/10.1002/adtp.202000073.

Dodd, Rebecca D., Amanda Scherer, Wesley Huang, Gavin R. McGivney, Wade R. Gutierrez, Emily A. Laverty, Kathleen A. Ashcraft, et al. “Tumor Subtype Determines Therapeutic Response to Chimeric Polypeptide Nanoparticle-based Chemotherapy in Pten-deleted Mouse Models of Sarcoma.” Clin Cancer Res 26, no. 18 (September 15, 2020): 5036–47. https://doi.org/10.1158/1078-0432.CCR-19-2597.

Dzuricky, Michael, Bradley A. Rogers, Abdulla Shahid, Paul S. Cremer, and Ashutosh Chilkoti. “De novo engineering of intracellular condensates using artificial disordered proteins.” Nature Chemistry 12, no. 9 (September 2020): 814–25. https://doi.org/10.1038/s41557-020-0511-7.

Gilroy, C. A., M. E. Capozzi, A. K. Varanko, J. Tong, D. A. D’Alessio, J. E. Campbell, and A. Chilkoti. “Sustained release of a GLP-1 and FGF21 dual agonist from an injectable depot protects mice from obesity and hyperglycemia.” Sci Adv 6, no. 35 (August 2020): eaaz9890. https://doi.org/10.1126/sciadv.aaz9890.

Zeng, Xiangze, Alex S. Holehouse, Ashutosh Chilkoti, Tanja Mittag, and Rohit V. Pappu. “Connecting Coil-to-Globule Transitions to Full Phase Diagrams for Intrinsically Disordered Proteins.” Biophysical Journal 119, no. 2 (July 2020): 402–18. https://doi.org/10.1016/j.bpj.2020.06.014.

Cruz, Daniela F., Cassio M. Fontes, Daria Semeniak, Jiani Huang, Angus Hucknall, Ashutosh Chilkoti, and Maiken H. Mikkelsen. “Ultrabright Fluorescence Readout of an Inkjet-Printed Immunoassay Using Plasmonic Nanogap Cavities.” Nano Letters 20, no. 6 (June 2020): 4330–36. https://doi.org/10.1021/acs.nanolett.0c01051.

Varanko, Anastasia K., Jonathan C. Su, and Ashutosh Chilkoti. “Elastin-Like Polypeptides for Biomedical Applications.” Annual Review of Biomedical Engineering 22 (June 2020): 343–69. https://doi.org/10.1146/annurev-bioeng-092419-061127.

Banskota, Samagya, Soumen Saha, Jayanta Bhattacharya, Nadia Kirmani, Parisa Yousefpour, Michael Dzuricky, Nikita Zakharov, et al. “Genetically Encoded Stealth Nanoparticles of a Zwitterionic Polypeptide-Paclitaxel Conjugate Have a Wider Therapeutic Window than Abraxane in Multiple Tumor Models.” Nano Lett 20, no. 4 (April 8, 2020): 2396–2409. https://doi.org/10.1021/acs.nanolett.9b05094.

Roberts, Stefan, Vincent Miao, Simone Costa, Joseph Simon, Garrett Kelly, Tejank Shah, Stefan Zauscher, and Ashutosh Chilkoti. “Complex microparticle architectures from stimuli-responsive intrinsically disordered proteins.” Nature Communications 11, no. 1 (March 2020): 1342. https://doi.org/10.1038/s41467-020-15128-9.

Saha, Soumen, Samagya Banskota, Stefan Roberts, Nadia Kirmani, and Ashutosh Chilkoti. “Engineering the Architecture of Elastin-Like Polypeptides: From Unimers to Hierarchical Self-Assembly.” Advanced Therapeutics 3, no. 3 (March 2020): 1900164. https://doi.org/10.1002/adtp.201900164.

Williams, Nicholas X., Nathan Watson, Daniel Y. Joh, Ashutosh Chilkoti, and Aaron D. Franklin. “Aerosol jet printing of biological inks by ultrasonic delivery.” Biofabrication 12, no. 2 (February 2020): 025004. https://doi.org/10.1088/1758-5090/ab5cf5.

Varanko, Anastasia, Soumen Saha, and Ashutosh Chilkoti. “Recent trends in protein and peptide-based biomaterials for advanced drug delivery.” Advanced Drug Delivery Reviews 156 (January 2020): 133–87. https://doi.org/10.1016/j.addr.2020.08.008.

Heggestad, Jacob T., Cassio M. Fontes, Daniel Y. Joh, Angus M. Hucknall, and Ashutosh Chilkoti. “In Pursuit of Zero 2.0: Recent Developments in Nonfouling Polymer Brushes for Immunoassays.” Advanced Materials (Deerfield Beach, Fla.) 32, no. 2 (January 2020): e1903285. https://doi.org/10.1002/adma.201903285.

Wang, Jing, Junseon Min, Seyed Ali Eghtesadi, Ravi S. Kane, and Ashutosh Chilkoti. “Quantitative Study of the Interaction of Multivalent Ligand-Modified Nanoparticles with Breast Cancer Cells with Tunable Receptor Density.” ACS Nano 14, no. 1 (January 2020): 372–83. https://doi.org/10.1021/acsnano.9b05689.