Publications
2017
Han, Wei, Ashutosh Chilkoti, and Gabriel P. López. “Self-assembled hybrid elastin-like polypeptide/silica nanoparticles enable triggered drug release.” Nanoscale 9, no. 18 (May 2017): 6178–86. https://doi.org/10.1039/c7nr00172j.
Bhattacharyya, Jayanta, Isaac Weitzhandler, Shihan Bryan Ho, Jonathan R. McDaniel, Xinghai Li, Lei Tang, Jinyao Liu, Mark Dewhirst, and Ashutosh Chilkoti. “Encapsulating a Hydrophilic Chemotherapeutic into Rod-like Nanoparticles of a Genetically Encoded Asymmetric Triblock Polypeptide Improves its Efficacy.” Adv Funct Mater 27, no. 12 (March 24, 2017). https://doi.org/10.1002/adfm.201605421.
Weinberger, A., V. Walter, S. R. MacEwan, T. Schmatko, P. Muller, A. P. Schroder, A. Chilkoti, and C. M. Marques. “Cargo self-assembly rescues affinity of cell-penetrating peptides to lipid membranes.” Scientific Reports 7 (March 6, 2017). https://doi.org/10.1038/srep43963.
Widder, Katharina, Sarah R. MacEwan, Elisabeth Garanger, Vanesa Núñez, Sébastien Lecommandoux, Ashutosh Chilkoti, and Dariush Hinderberger. “Characterisation of hydration and nanophase separation during the temperature response in hydrophobic/hydrophilic elastin-like polypeptide (ELP) diblock copolymers.” Soft Matter 13, no. 9 (March 2017): 1816–22. https://doi.org/10.1039/c6sm02427k.
Ozer, Imran, and Ashutosh Chilkoti. “Site-Specific and Stoichiometric Stealth Polymer Conjugates of Therapeutic Peptides and Proteins.” Bioconjugate Chemistry 28, no. 3 (March 2017): 713–23. https://doi.org/10.1021/acs.bioconjchem.6b00652.
Wang, Jing, Sarah R. MacEwan, and Ashutosh Chilkoti. “Quantitative Mapping of the Spatial Distribution of Nanoparticles in Endo-Lysosomes by Local pH.” Nano Letters 17, no. 2 (February 2017): 1226–32. https://doi.org/10.1021/acs.nanolett.6b05041.
MacEwan, Sarah R., Isaac Weitzhandler, Ingo Hoffmann, Jan Genzer, Michael Gradzielski, and Ashutosh Chilkoti. “Phase Behavior and Self-Assembly of Perfectly Sequence-Defined and Monodisperse Multiblock Copolypeptides.” Biomacromolecules 18, no. 2 (February 2017): 599–609. https://doi.org/10.1021/acs.biomac.6b01759.
Joh, Daniel Y., Felicia McGuire, Roozbeh Abedini-Nassab, Joseph B. Andrews, Rohan K. Achar, Zackary Zimmers, Darush Mozhdehi, et al. “Poly(oligo(ethylene glycol) methyl ether methacrylate) Brushes on High-κ Metal Oxide Dielectric Surfaces for Bioelectrical Environments.” ACS Applied Materials & Interfaces 9, no. 6 (February 2017): 5522–29. https://doi.org/10.1021/acsami.6b15836.
Banskota, Samagya, Parisa Yousefpour, and Ashutosh Chilkoti. “Cell-Based Biohybrid Drug Delivery Systems: The Best of the Synthetic and Natural Worlds.” Macromolecular Bioscience 17, no. 1 (January 2017). https://doi.org/10.1002/mabi.201600361.
Simon, Joseph R., Nick J. Carroll, Michael Rubinstein, Ashutosh Chilkoti, and Gabriel P. López. “Programming molecular self-assembly of intrinsically disordered proteins containing sequences of low complexity.” Nature Chemistry, 2017. https://doi.org/10.1038/nchem.2715.
Luginbuhl, Kelli M., Jeffrey L. Schaal, Bret Umstead, Eric M. Mastria, Xinghai Li, Samagya Banskota, Susan Arnold, Mark Feinglos, David D’Alessio, and Ashutosh Chilkoti. “One-week glucose control via zero-order release kinetics from an injectable depot of glucagon-like peptide-1 fused to a thermosensitive biopolymer.” Nat Biomed Eng 1 (2017). https://doi.org/10.1038/s41551-017-0078.
Gonzalez, Mark A., Joseph R. Simon, Ali Ghoorchian, Zachary Scholl, Shaoting Lin, Michael Rubinstein, Piotr Marszalek, Ashutosh Chilkoti, Gabriel P. López, and Xuanhe Zhao. “Strong, Tough, Stretchable, and Self-Adhesive Hydrogels from Intrinsically Unstructured Proteins.” Advanced Materials, 2017. https://doi.org/10.1002/adma.201604743.
Roberts, S., S. Costa, J. Schaal, J. R. Simon, M. Dzuricky, F. G. Quiroz, and A. Chilkoti. “2.5 Elastin-like polypeptides.” In Comprehensive Biomaterials II, 90–108, 2017. https://doi.org/10.1016/B978-0-12-803581-8.09308-5.
2016
Kwok, Kevin W. H., Wu Dong, Stella M. Marinakos, Jie Liu, Ashutosh Chilkoti, Mark R. Wiesner, Melissa Chernick, and David E. Hinton. “Silver nanoparticle toxicity is related to coating materials and disruption of sodium concentration regulation.” Nanotoxicology 10, no. 9 (November 2016): 1306–17. https://doi.org/10.1080/17435390.2016.1206150.
Abedini-Nassab, Roozbeh, Daniel Y. Joh, Faris Albarghouthi, Ashutosh Chilkoti, David M. Murdoch, and Benjamin B. Yellen. “Magnetophoretic transistors in a tri-axial magnetic field.” Lab Chip 16, no. 21 (October 18, 2016): 4181–88. https://doi.org/10.1039/c6lc00878j.
Gilroy, Caslin A., Kelli M. Luginbuhl, and Ashutosh Chilkoti. “Controlled release of biologics for the treatment of type 2 diabetes.” Journal of Controlled Release : Official Journal of the Controlled Release Society 240 (October 2016): 151–64. https://doi.org/10.1016/j.jconrel.2015.12.002.
Pham, An T., Ryohei Seto, Johannes Schönke, Daniel Y. Joh, Ashutosh Chilkoti, Eliot Fried, and Benjamin B. Yellen. “Crystallization kinetics of binary colloidal monolayers.” Soft Matter 12, no. 37 (October 2016): 7735–46. https://doi.org/10.1039/c6sm01072e.
Pang, Yan, Jinyao Liu, Yizhi Qi, Xinghai Li, and Ashutosh Chilkoti. “A Modular Method for the High-Yield Synthesis of Site-Specific Protein-Polymer Therapeutics.” Angewandte Chemie (International Ed. in English) 55, no. 35 (August 2016): 10296–300. https://doi.org/10.1002/anie.201604661.
Liu, Jinyao, Yan Pang, Jayanta Bhattacharyya, Wenge Liu, Isaac Weitzhandler, Xinghai Li, and Ashutosh Chilkoti. “Developing Precisely Defined Drug-Loaded Nanoparticles by Ring-Opening Polymerization of a Paclitaxel Prodrug.” Advanced Healthcare Materials 5, no. 15 (August 2016): 1868–73. https://doi.org/10.1002/adhm.201600230.
Abedini-Nassab, Roozbeh, Daniel Y. Joh, Melissa Van Heest, Cody Baker, Ashutosh Chilkoti, David M. Murdoch, and Benjamin B. Yellen. “Magnetophoretic Conductors and Diodes in a 3D Magnetic Field.” Adv Funct Mater 26, no. 22 (June 14, 2016): 4026–34. https://doi.org/10.1002/adfm.201503898.
Li, Linying, Chia-Kuei Mo, Ashutosh Chilkoti, Gabriel P. Lopez, and Nick J. Carroll. “Creating cellular patterns using genetically engineered, gold- and cell-binding polypeptides.” Biointerphases 11, no. 2 (June 2016): 021009. https://doi.org/10.1116/1.4952452.
Schaal, Jeffrey L., Xinghai Li, Eric Mastria, Jayanta Bhattacharyya, Michael R. Zalutsky, Ashutosh Chilkoti, and Wenge Liu. “Injectable polypeptide micelles that form radiation crosslinked hydrogels in situ for intratumoral radiotherapy.” J Control Release 228 (April 28, 2016): 58–66. https://doi.org/10.1016/j.jconrel.2016.02.040.
Tang, Nicholas C., and Ashutosh Chilkoti. “Combinatorial codon scrambling enables scalable gene synthesis and amplification of repetitive proteins.” Nature Materials 15, no. 4 (April 2016): 419–24. https://doi.org/10.1038/nmat4521.
Nawroth, Jonas F., Jonathan R. McDaniel, Ashutosh Chilkoti, Rainer Jordan, and Robert Luxenhofer. “Maleimide-Functionalized Poly(2-Oxazoline)s and Their Conjugation to Elastin-Like Polypeptides.” Macromolecular Bioscience 16, no. 3 (March 2016): 322–33. https://doi.org/10.1002/mabi.201500376.
Mukerji, Ratul, Jeffrey Schaal, Xinghai Li, Jayanta Bhattacharyya, Daisuke Asai, Michael R. Zalutsky, Ashutosh Chilkoti, and Wenge Liu. “Spatiotemporally photoradiation-controlled intratumoral depot for combination of brachytherapy and photodynamic therapy for solid tumor.” Biomaterials 79 (February 2016): 79–87. https://doi.org/10.1016/j.biomaterials.2015.11.064.