Publications

Wang, Jing, Jayanta Bhattacharyya, Eric Mastria, and Ashutosh Chilkoti. “A quantitative study of the intracellular fate of pH-responsive doxorubicin-polypeptide nanoparticles.” J Control Release 260 (August 28, 2017): 100–110. https://doi.org/10.1016/j.jconrel.2017.05.032.

Joh, Daniel Y., Angus M. Hucknall, Qingshan Wei, Kelly A. Mason, Margaret L. Lund, Cassio M. Fontes, Ryan T. Hill, et al. “Inkjet-printed point-of-care immunoassay on a nanoscale polymer brush enables subpicomolar detection of analytes in blood.” Proc Natl Acad Sci U S A 114, no. 34 (August 22, 2017): E7054–62. https://doi.org/10.1073/pnas.1703200114.

Weitzhandler, Isaac, Michael Dzuricky, Ingo Hoffmann, Felipe Garcia Quiroz, Michael Gradzielski, and Ashutosh Chilkoti. “Micellar Self-Assembly of Recombinant Resilin-/Elastin-Like Block Copolypeptides.” Biomacromolecules 18, no. 8 (August 2017): 2419–26. https://doi.org/10.1021/acs.biomac.7b00589.

MacEwan, Sarah R., and Ashutosh Chilkoti. “From Composition to Cure: A Systems Engineering Approach to Anticancer Drug Carriers.” Angewandte Chemie (International Ed. in English) 56, no. 24 (June 2017): 6712–33. https://doi.org/10.1002/anie.201610819.

Tang, Lei, Luis A. Navarro, Ashutosh Chilkoti, and Stefan Zauscher. “High-Molecular-Weight Polynucleotides by Transferase-Catalyzed Living Chain-Growth Polycondensation.” Angewandte Chemie (International Ed. in English) 56, no. 24 (June 2017): 6778–82. https://doi.org/10.1002/anie.201700991.

Han, Wei, Ashutosh Chilkoti, and Gabriel P. López. “Self-assembled hybrid elastin-like polypeptide/silica nanoparticles enable triggered drug release.” Nanoscale 9, no. 18 (May 2017): 6178–86. https://doi.org/10.1039/c7nr00172j.

Bhattacharyya, Jayanta, Isaac Weitzhandler, Shihan Bryan Ho, Jonathan R. McDaniel, Xinghai Li, Lei Tang, Jinyao Liu, Mark Dewhirst, and Ashutosh Chilkoti. “Encapsulating a Hydrophilic Chemotherapeutic into Rod-like Nanoparticles of a Genetically Encoded Asymmetric Triblock Polypeptide Improves its Efficacy.” Adv Funct Mater 27, no. 12 (March 24, 2017). https://doi.org/10.1002/adfm.201605421.

Weinberger, A., V. Walter, S. R. MacEwan, T. Schmatko, P. Muller, A. P. Schroder, A. Chilkoti, and C. M. Marques. “Cargo self-assembly rescues affinity of cell-penetrating peptides to lipid membranes.” Scientific Reports 7 (March 6, 2017). https://doi.org/10.1038/srep43963.

Widder, Katharina, Sarah R. MacEwan, Elisabeth Garanger, Vanesa Núñez, Sébastien Lecommandoux, Ashutosh Chilkoti, and Dariush Hinderberger. “Characterisation of hydration and nanophase separation during the temperature response in hydrophobic/hydrophilic elastin-like polypeptide (ELP) diblock copolymers.” Soft Matter 13, no. 9 (March 2017): 1816–22. https://doi.org/10.1039/c6sm02427k.

Ozer, Imran, and Ashutosh Chilkoti. “Site-Specific and Stoichiometric Stealth Polymer Conjugates of Therapeutic Peptides and Proteins.” Bioconjugate Chemistry 28, no. 3 (March 2017): 713–23. https://doi.org/10.1021/acs.bioconjchem.6b00652.

Wang, Jing, Sarah R. MacEwan, and Ashutosh Chilkoti. “Quantitative Mapping of the Spatial Distribution of Nanoparticles in Endo-Lysosomes by Local pH.” Nano Letters 17, no. 2 (February 2017): 1226–32. https://doi.org/10.1021/acs.nanolett.6b05041.

MacEwan, Sarah R., Isaac Weitzhandler, Ingo Hoffmann, Jan Genzer, Michael Gradzielski, and Ashutosh Chilkoti. “Phase Behavior and Self-Assembly of Perfectly Sequence-Defined and Monodisperse Multiblock Copolypeptides.” Biomacromolecules 18, no. 2 (February 2017): 599–609. https://doi.org/10.1021/acs.biomac.6b01759.

Joh, Daniel Y., Felicia McGuire, Roozbeh Abedini-Nassab, Joseph B. Andrews, Rohan K. Achar, Zackary Zimmers, Darush Mozhdehi, et al. “Poly(oligo(ethylene glycol) methyl ether methacrylate) Brushes on High-κ Metal Oxide Dielectric Surfaces for Bioelectrical Environments.” ACS Applied Materials & Interfaces 9, no. 6 (February 2017): 5522–29. https://doi.org/10.1021/acsami.6b15836.

Roberts, S., S. Costa, J. Schaal, J. R. Simon, M. Dzuricky, F. G. Quiroz, and A. Chilkoti. “2.5 Elastin-like polypeptides.” In Comprehensive Biomaterials II, 90–108, 2017. https://doi.org/10.1016/B978-0-12-803581-8.09308-5.

Banskota, Samagya, Parisa Yousefpour, and Ashutosh Chilkoti. “Cell-Based Biohybrid Drug Delivery Systems: The Best of the Synthetic and Natural Worlds.” Macromolecular Bioscience 17, no. 1 (January 2017). https://doi.org/10.1002/mabi.201600361.

Simon, Joseph R., Nick J. Carroll, Michael Rubinstein, Ashutosh Chilkoti, and Gabriel P. López. “Programming molecular self-assembly of intrinsically disordered proteins containing sequences of low complexity.” Nature Chemistry, 2017. https://doi.org/10.1038/nchem.2715.

Luginbuhl, Kelli M., Jeffrey L. Schaal, Bret Umstead, Eric M. Mastria, Xinghai Li, Samagya Banskota, Susan Arnold, Mark Feinglos, David D’Alessio, and Ashutosh Chilkoti. “One-week glucose control via zero-order release kinetics from an injectable depot of glucagon-like peptide-1 fused to a thermosensitive biopolymer.” Nat Biomed Eng 1 (2017). https://doi.org/10.1038/s41551-017-0078.

Gonzalez, Mark A., Joseph R. Simon, Ali Ghoorchian, Zachary Scholl, Shaoting Lin, Michael Rubinstein, Piotr Marszalek, Ashutosh Chilkoti, Gabriel P. López, and Xuanhe Zhao. “Strong, Tough, Stretchable, and Self-Adhesive Hydrogels from Intrinsically Unstructured Proteins.” Advanced Materials, 2017. https://doi.org/10.1002/adma.201604743.

Kwok, Kevin W. H., Wu Dong, Stella M. Marinakos, Jie Liu, Ashutosh Chilkoti, Mark R. Wiesner, Melissa Chernick, and David E. Hinton. “Silver nanoparticle toxicity is related to coating materials and disruption of sodium concentration regulation.” Nanotoxicology 10, no. 9 (November 2016): 1306–17. https://doi.org/10.1080/17435390.2016.1206150.

Abedini-Nassab, Roozbeh, Daniel Y. Joh, Faris Albarghouthi, Ashutosh Chilkoti, David M. Murdoch, and Benjamin B. Yellen. “Magnetophoretic transistors in a tri-axial magnetic field.” Lab Chip 16, no. 21 (October 18, 2016): 4181–88. https://doi.org/10.1039/c6lc00878j.

Gilroy, Caslin A., Kelli M. Luginbuhl, and Ashutosh Chilkoti. “Controlled release of biologics for the treatment of type 2 diabetes.” Journal of Controlled Release : Official Journal of the Controlled Release Society 240 (October 2016): 151–64. https://doi.org/10.1016/j.jconrel.2015.12.002.

Pham, An T., Ryohei Seto, Johannes Schönke, Daniel Y. Joh, Ashutosh Chilkoti, Eliot Fried, and Benjamin B. Yellen. “Crystallization kinetics of binary colloidal monolayers.” Soft Matter 12, no. 37 (October 2016): 7735–46. https://doi.org/10.1039/c6sm01072e.

Liu, Jinyao, Yan Pang, Jayanta Bhattacharyya, Wenge Liu, Isaac Weitzhandler, Xinghai Li, and Ashutosh Chilkoti. “Developing Precisely Defined Drug-Loaded Nanoparticles by Ring-Opening Polymerization of a Paclitaxel Prodrug.” Advanced Healthcare Materials 5, no. 15 (August 2016): 1868–73. https://doi.org/10.1002/adhm.201600230.

Pang, Yan, Jinyao Liu, Yizhi Qi, Xinghai Li, and Ashutosh Chilkoti. “A Modular Method for the High-Yield Synthesis of Site-Specific Protein-Polymer Therapeutics.” Angewandte Chemie (International Ed. in English) 55, no. 35 (August 2016): 10296–300. https://doi.org/10.1002/anie.201604661.

Abedini-Nassab, Roozbeh, Daniel Y. Joh, Melissa Van Heest, Cody Baker, Ashutosh Chilkoti, David M. Murdoch, and Benjamin B. Yellen. “Magnetophoretic Conductors and Diodes in a 3D Magnetic Field.” Adv Funct Mater 26, no. 22 (June 14, 2016): 4026–34. https://doi.org/10.1002/adfm.201503898.