Publications

Varanko, Anastasia, Soumen Saha, and Ashutosh Chilkoti. “Recent trends in protein and peptide-based biomaterials for advanced drug delivery.” Advanced Drug Delivery Reviews 156 (January 2020): 133–87. https://doi.org/10.1016/j.addr.2020.08.008.

Wang, Jing, Soumen Saha, Jeffrey L. Schaal, Parisa Yousefpour, Xinghai Li, and Ashutosh Chilkoti. “Heuristics for the Optimal Presentation of Bioactive Peptides on Polypeptide Micelles.” Nano Letters 19, no. 11 (November 2019): 7977–87. https://doi.org/10.1021/acs.nanolett.9b03141.

Willems, Lione, Larissa van Westerveld, Stefan Roberts, Isaac Weitzhandler, Carlos Calcines Cruz, Armando Hernandez-Garcia, Ashutosh Chilkoti, Enrico Mastrobattista, John van der Oost, and Renko de Vries. “Nature of Amorphous Hydrophilic Block Affects Self-Assembly of an Artificial Viral Coat Polypeptide.” Biomacromolecules 20, no. 10 (October 2019): 3641–47. https://doi.org/10.1021/acs.biomac.9b00512.

Garcia Quiroz, Felipe, Nan K. Li, Stefan Roberts, Patrick Weber, Michael Dzuricky, Isaac Weitzhandler, Yaroslava G. Yingling, and Ashutosh Chilkoti. “Intrinsically disordered proteins access a range of hysteretic phase separation behaviors.” Science Advances 5, no. 10 (October 2019): eaax5177. https://doi.org/10.1126/sciadv.aax5177.

Dai, Zhuojun, Anna J. Lee, Stefan Roberts, Tatyana A. Sysoeva, Shuqiang Huang, Michael Dzuricky, Xiaoyu Yang, et al. “Versatile biomanufacturing through stimulus-responsive cell-material feedback.” Nature Chemical Biology 15, no. 10 (October 2019): 1017–24. https://doi.org/10.1038/s41589-019-0357-8.

Manzari, Mandana T., Gray R. Anderson, Kevin H. Lin, Ryan S. Soderquist, Merve Çakir, Mitchell Zhang, Chandler E. Moore, et al. “Genomically informed small-molecule drugs overcome resistance to a sustained-release formulation of an engineered death receptor agonist in patient-derived tumor models.” Sci Adv 5, no. 9 (September 2019): eaaw9162. https://doi.org/10.1126/sciadv.aaw9162.

Dzuricky, Michael, Sinan Xiong, Patrick Weber, and Ashutosh Chilkoti. “Avidity and Cell Uptake of Integrin-Targeting Polypeptide Micelles is Strongly Shape-Dependent.” Nano Letters 19, no. 9 (September 2019): 6124–32. https://doi.org/10.1021/acs.nanolett.9b02095.

Simon, Joseph R., Seyed Ali Eghtesadi, Michael Dzuricky, Lingchong You, and Ashutosh Chilkoti. “Engineered Ribonucleoprotein Granules Inhibit Translation in Protocells.” Molecular Cell 75, no. 1 (July 2019): 66-75.e5. https://doi.org/10.1016/j.molcel.2019.05.010.

Varanko, Anastasia K., and Ashutosh Chilkoti. “Molecular and Materials Engineering for Delivery of Peptide Drugs to Treat Type 2 Diabetes.” Advanced Healthcare Materials 8, no. 12 (June 2019): e1801509. https://doi.org/10.1002/adhm.201801509.

Willems, Lione, Stefan Roberts, Isaac Weitzhandler, Ashutosh Chilkoti, Enrico Mastrobattista, John van der Oost, and Renko de Vries. “Inducible Fibril Formation of Silk-Elastin Diblocks.” ACS Omega 4, no. 5 (May 2019): 9135–43. https://doi.org/10.1021/acsomega.9b01025.

Koc, Julian, Tomer Simovich, Eric Schönemann, Ashutosh Chilkoti, Harrison Gardner, Geoffrey W. Swain, Kelli Hunsucker, André Laschewsky, and Axel Rosenhahn. “Sediment challenge to promising ultra-low fouling hydrophilic surfaces in the marine environment.” Biofouling 35, no. 4 (April 2019): 454–62. https://doi.org/10.1080/08927014.2019.1611790.

Joh, Daniel Y., Zackary Zimmers, Manav Avlani, Jacob T. Heggestad, Hakan B. Aydin, Nancy Ganson, Shourya Kumar, et al. “Architectural Modification of Conformal PEG-Bottlebrush Coatings Minimizes Anti-PEG Antigenicity While Preserving Stealth Properties.” Adv Healthc Mater 8, no. 8 (April 2019): e1801177. https://doi.org/10.1002/adhm.201801177.

Yousefpour, Parisa, Lucie Ahn, Joel Tewksbury, Soumen Saha, Simone A. Costa, Joseph J. Bellucci, Xinghai Li, and Ashutosh Chilkoti. “Conjugate of Doxorubicin to Albumin-Binding Peptide Outperforms Aldoxorubicin.” Small (Weinheim an Der Bergstrasse, Germany) 15, no. 12 (March 2019): e1804452. https://doi.org/10.1002/smll.201804452.

Banskota, Samagya, Parisa Yousefpour, Nadia Kirmani, Xinghai Li, and Ashutosh Chilkoti. “Long circulating genetically encoded intrinsically disordered zwitterionic polypeptides for drug delivery.” Biomaterials 192 (February 2019): 475–85. https://doi.org/10.1016/j.biomaterials.2018.11.012.

Fontes, Cassio M., Rohan K. Achar, Daniel Y. Joh, Imran Ozer, Somnath Bhattacharjee, Angus Hucknall, and Ashutosh Chilkoti. “Engineering the Surface Properties of a Zwitterionic Polymer Brush to Enable the Simple Fabrication of Inkjet-Printed Point-of-Care Immunoassays.” Langmuir : The ACS Journal of Surfaces and Colloids 35, no. 5 (February 2019): 1379–90. https://doi.org/10.1021/acs.langmuir.8b01597.

Mozhdehi, Davoud, Kelli M. Luginbuhl, Michael Dzuricky, Simone A. Costa, Sinan Xiong, Fred C. Huang, Mae M. Lewis, Stephanie R. Zelenetz, Christian D. Colby, and Ashutosh Chilkoti. “Genetically Encoded Cholesterol-Modified Polypeptides.” Journal of the American Chemical Society 141, no. 2 (January 2019): 945–51. https://doi.org/10.1021/jacs.8b10687.

Deshpande, Sonal, Yunqi Yang, Ashutosh Chilkoti, and Stefan Zauscher. “Enzymatic synthesis and modification of high molecular weight DNA using terminal deoxynucleotidyl transferase.,” 627:163–88, 2019. https://doi.org/10.1016/bs.mie.2019.07.044.

Costa, Simone A., Davoud Mozhdehi, Michael J. Dzuricky, Farren J. Isaacs, Eric M. Brustad, and Ashutosh Chilkoti. “Active Targeting of Cancer Cells by Nanobody Decorated Polypeptide Micelle with Bio-orthogonally Conjugated Drug.” Nano Letters 19, no. 1 (January 2019): 247–54. https://doi.org/10.1021/acs.nanolett.8b03837.

Roberts, Stefan, Tyler S. Harmon, Jeffrey L. Schaal, Vincent Miao, Kan Jonathan Li, Andrew Hunt, Yi Wen, et al. “Author Correction: Injectable tissue integrating networks from recombinant polypeptides with tunable order.” Nat Mater 17, no. 12 (December 2018): 1164. https://doi.org/10.1038/s41563-018-0233-z.

Roberts, Stefan, Tyler S. Harmon, Jeffrey L. Schaal, Vincent Miao, Kan Jonathan Li, Andrew Hunt, Yi Wen, et al. “Injectable tissue integrating networks from recombinant polypeptides with tunable order.” Nat Mater 17, no. 12 (December 2018): 1154–63. https://doi.org/10.1038/s41563-018-0182-6.

Yousefpour, Parisa, Jonathan R. McDaniel, Varun Prasad, Lucie Ahn, Xinghai Li, Rishi Subrahmanyan, Isaac Weitzhandler, Steven Suter, and Ashutosh Chilkoti. “Genetically Encoding Albumin Binding into Chemotherapeutic-loaded Polypeptide Nanoparticles Enhances Their Antitumor Efficacy.” Nano Letters 18, no. 12 (December 2018): 7784–93. https://doi.org/10.1021/acs.nanolett.8b03558.

Ruff, Kiersten M., Stefan Roberts, Ashutosh Chilkoti, and Rohit V. Pappu. “Advances in Understanding Stimulus-Responsive Phase Behavior of Intrinsically Disordered Protein Polymers.” Journal of Molecular Biology 430, no. 23 (November 2018): 4619–35. https://doi.org/10.1016/j.jmb.2018.06.031.

Gu, Renpeng, Thomas Oweida, Yaroslava G. Yingling, Ashutosh Chilkoti, and Stefan Zauscher. “Enzymatic Synthesis of Nucleobase-Modified Single-Stranded DNA Offers Tunable Resistance to Nuclease Degradation.” Biomacromolecules 19, no. 8 (August 2018): 3525–35. https://doi.org/10.1021/acs.biomac.8b00816.

Li, Nan K., Stefan Roberts, Felipe Garcia Quiroz, Ashutosh Chilkoti, and Yaroslava G. Yingling. “Sequence Directionality Dramatically Affects LCST Behavior of Elastin-Like Polypeptides.” Biomacromolecules 19, no. 7 (July 2018): 2496–2505. https://doi.org/10.1021/acs.biomac.8b00099.

Gilroy, Caslin A., Stefan Roberts, and Ashutosh Chilkoti. “Fusion of fibroblast growth factor 21 to a thermally responsive biopolymer forms an injectable depot with sustained anti-diabetic action.” Journal of Controlled Release : Official Journal of the Controlled Release Society 277 (May 2018): 154–64. https://doi.org/10.1016/j.jconrel.2018.03.015.