Publications
2017
Banskota, Samagya, Parisa Yousefpour, and Ashutosh Chilkoti. “Cell-Based Biohybrid Drug Delivery Systems: The Best of the Synthetic and Natural Worlds.” Macromolecular Bioscience 17, no. 1 (January 2017). https://doi.org/10.1002/mabi.201600361.
Simon, Joseph R., Nick J. Carroll, Michael Rubinstein, Ashutosh Chilkoti, and Gabriel P. López. “Programming molecular self-assembly of intrinsically disordered proteins containing sequences of low complexity.” Nature Chemistry, 2017. https://doi.org/10.1038/nchem.2715.
2016
Kwok, Kevin W. H., Wu Dong, Stella M. Marinakos, Jie Liu, Ashutosh Chilkoti, Mark R. Wiesner, Melissa Chernick, and David E. Hinton. “Silver nanoparticle toxicity is related to coating materials and disruption of sodium concentration regulation.” Nanotoxicology 10, no. 9 (November 2016): 1306–17. https://doi.org/10.1080/17435390.2016.1206150.
Abedini-Nassab, Roozbeh, Daniel Y. Joh, Faris Albarghouthi, Ashutosh Chilkoti, David M. Murdoch, and Benjamin B. Yellen. “Magnetophoretic transistors in a tri-axial magnetic field.” Lab Chip 16, no. 21 (October 18, 2016): 4181–88. https://doi.org/10.1039/c6lc00878j.
Pham, An T., Ryohei Seto, Johannes Schönke, Daniel Y. Joh, Ashutosh Chilkoti, Eliot Fried, and Benjamin B. Yellen. “Crystallization kinetics of binary colloidal monolayers.” Soft Matter 12, no. 37 (October 2016): 7735–46. https://doi.org/10.1039/c6sm01072e.
Gilroy, Caslin A., Kelli M. Luginbuhl, and Ashutosh Chilkoti. “Controlled release of biologics for the treatment of type 2 diabetes.” Journal of Controlled Release : Official Journal of the Controlled Release Society 240 (October 2016): 151–64. https://doi.org/10.1016/j.jconrel.2015.12.002.
Pang, Yan, Jinyao Liu, Yizhi Qi, Xinghai Li, and Ashutosh Chilkoti. “A Modular Method for the High-Yield Synthesis of Site-Specific Protein-Polymer Therapeutics.” Angewandte Chemie (International Ed. in English) 55, no. 35 (August 2016): 10296–300. https://doi.org/10.1002/anie.201604661.
Liu, Jinyao, Yan Pang, Jayanta Bhattacharyya, Wenge Liu, Isaac Weitzhandler, Xinghai Li, and Ashutosh Chilkoti. “Developing Precisely Defined Drug-Loaded Nanoparticles by Ring-Opening Polymerization of a Paclitaxel Prodrug.” Advanced Healthcare Materials 5, no. 15 (August 2016): 1868–73. https://doi.org/10.1002/adhm.201600230.
Abedini-Nassab, Roozbeh, Daniel Y. Joh, Melissa Van Heest, Cody Baker, Ashutosh Chilkoti, David M. Murdoch, and Benjamin B. Yellen. “Magnetophoretic Conductors and Diodes in a 3D Magnetic Field.” Adv Funct Mater 26, no. 22 (June 14, 2016): 4026–34. https://doi.org/10.1002/adfm.201503898.
Li, Linying, Chia-Kuei Mo, Ashutosh Chilkoti, Gabriel P. Lopez, and Nick J. Carroll. “Creating cellular patterns using genetically engineered, gold- and cell-binding polypeptides.” Biointerphases 11, no. 2 (June 2016): 021009. https://doi.org/10.1116/1.4952452.
Schaal, Jeffrey L., Xinghai Li, Eric Mastria, Jayanta Bhattacharyya, Michael R. Zalutsky, Ashutosh Chilkoti, and Wenge Liu. “Injectable polypeptide micelles that form radiation crosslinked hydrogels in situ for intratumoral radiotherapy.” J Control Release 228 (April 28, 2016): 58–66. https://doi.org/10.1016/j.jconrel.2016.02.040.
Tang, Nicholas C., and Ashutosh Chilkoti. “Combinatorial codon scrambling enables scalable gene synthesis and amplification of repetitive proteins.” Nature Materials 15, no. 4 (April 2016): 419–24. https://doi.org/10.1038/nmat4521.
Nawroth, Jonas F., Jonathan R. McDaniel, Ashutosh Chilkoti, Rainer Jordan, and Robert Luxenhofer. “Maleimide-Functionalized Poly(2-Oxazoline)s and Their Conjugation to Elastin-Like Polypeptides.” Macromolecular Bioscience 16, no. 3 (March 2016): 322–33. https://doi.org/10.1002/mabi.201500376.
Mukerji, Ratul, Jeffrey Schaal, Xinghai Li, Jayanta Bhattacharyya, Daisuke Asai, Michael R. Zalutsky, Ashutosh Chilkoti, and Wenge Liu. “Spatiotemporally photoradiation-controlled intratumoral depot for combination of brachytherapy and photodynamic therapy for solid tumor.” Biomaterials 79 (February 2016): 79–87. https://doi.org/10.1016/j.biomaterials.2015.11.064.
Qi, Yizhi, Antonina Simakova, Nancy J. Ganson, Xinghai Li, Kelli M. Luginbuhl, Imran Özer, Wenge Liu, Michael S. Hershfield, Krzysztof Matyjaszewski, and Ashutosh Chilkoti. “A brush-polymer conjugate of exendin-4 reduces blood glucose for up to five days and eliminates poly(ethylene glycol) antigenicity.” Nat Biomed Eng 1 (2016). https://doi.org/10.1038/s41551-016-0002.
Bhattacharyya, J., J. J. Bellucci, and A. Chilkoti. “Elastin-Like Polypeptides: Bio-Inspired Smart Polymers for Protein Purification, Drug Delivery and Tissue Engineering.” In Biomaterials from Nature for Advanced Devices and Therapies, 106–26, 2016. https://doi.org/10.1002/9781119126218.ch7.
2015
Bhattacharjee, Somnath, Wenge Liu, Wei-Han Wang, Isaac Weitzhandler, Xinghai Li, Yizhi Qi, Jinyao Liu, Yan Pang, Donald F. Hunt, and Ashutosh Chilkoti. “Site-Specific Zwitterionic Polymer Conjugates of a Protein Have Long Plasma Circulation.” Chembiochem : A European Journal of Chemical Biology 16, no. 17 (November 2015): 2451–55. https://doi.org/10.1002/cbic.201500439.
Quiroz, Felipe García, and Ashutosh Chilkoti. “Sequence heuristics to encode phase behaviour in intrinsically disordered protein polymers.” Nature Materials 14, no. 11 (November 2015): 1164–71. https://doi.org/10.1038/nmat4418.
Li, Nan K., William H. Fuss, Lei Tang, Renpeng Gu, Ashutosh Chilkoti, Stefan Zauscher, and Yaroslava G. Yingling. “Prediction of solvent-induced morphological changes of polyelectrolyte diblock copolymer micelles.” Soft Matter 11, no. 42 (November 2015): 8236–45. https://doi.org/10.1039/c5sm01742d.
Abedini-Nassab, Roozbeh, Daniel Y. Joh, Melissa A. Van Heest, John S. Yi, Cody Baker, Zohreh Taherifard, David M. Margolis, et al. “Characterizing the Switching Thresholds of Magnetophoretic Transistors.” Adv Mater 27, no. 40 (October 28, 2015): 6176–80. https://doi.org/10.1002/adma.201502352.
Qi, Yizhi, and Ashutosh Chilkoti. “Protein-polymer conjugation-moving beyond PEGylation.” Current Opinion in Chemical Biology 28 (October 2015): 181–93. https://doi.org/10.1016/j.cbpa.2015.08.009.
Garanger, E., S. R. MacEwan, O. Sandre, A. Brûlet, L. Bataille, A. Chilkoti, and S. Lecommandoux. “Structural Evolution of a Stimulus-Responsive Diblock Polypeptide Micelle by Temperature Tunable Compaction of its Core.” Macromolecules 48, no. 18 (September 22, 2015): 6617–27. https://doi.org/10.1021/acs.macromol.5b01371.
Roberts, Stefan, Michael Dzuricky, and Ashutosh Chilkoti. “Elastin-like polypeptides as models of intrinsically disordered proteins.” FEBS Letters 589, no. 19 Pt A (September 2015): 2477–86. https://doi.org/10.1016/j.febslet.2015.08.029.
Bhattacharyya, Jayanta, Joseph J. Bellucci, Isaac Weitzhandler, Jonathan R. McDaniel, Ivan Spasojevic, Xinghai Li, Chao-Chieh Lin, Jen-Tsan Ashley Chi, and Ashutosh Chilkoti. “A paclitaxel-loaded recombinant polypeptide nanoparticle outperforms Abraxane in multiple murine cancer models.” Nat Commun 6 (August 4, 2015): 7939. https://doi.org/10.1038/ncomms8939.
Han, Wei, Sarah R. MacEwan, Ashutosh Chilkoti, and Gabriel P. López. “Bio-inspired synthesis of hybrid silica nanoparticles templated from elastin-like polypeptide micelles.” Nanoscale 7, no. 28 (July 2015): 12038–44. https://doi.org/10.1039/c5nr01407g.