Publications

2015

Abedini-Nassab, Roozbeh, Daniel Y. Joh, Melissa A. Van Heest, John S. Yi, Cody Baker, Zohreh Taherifard, David M. Margolis, et al. “Characterizing the Switching Thresholds of Magnetophoretic Transistors.” Adv Mater 27, no. 40 (October 28, 2015): 6176–80. https://doi.org/10.1002/adma.201502352.

Qi, Yizhi, and Ashutosh Chilkoti. “Protein-polymer conjugation-moving beyond PEGylation.” Current Opinion in Chemical Biology 28 (October 2015): 181–93. https://doi.org/10.1016/j.cbpa.2015.08.009.

Garanger, E., S. R. MacEwan, O. Sandre, A. Brûlet, L. Bataille, A. Chilkoti, and S. Lecommandoux. “Structural Evolution of a Stimulus-Responsive Diblock Polypeptide Micelle by Temperature Tunable Compaction of its Core.” Macromolecules 48, no. 18 (September 22, 2015): 6617–27. https://doi.org/10.1021/acs.macromol.5b01371.

Roberts, Stefan, Michael Dzuricky, and Ashutosh Chilkoti. “Elastin-like polypeptides as models of intrinsically disordered proteins.” FEBS Letters 589, no. 19 Pt A (September 2015): 2477–86. https://doi.org/10.1016/j.febslet.2015.08.029.

Bhattacharyya, Jayanta, Joseph J. Bellucci, Isaac Weitzhandler, Jonathan R. McDaniel, Ivan Spasojevic, Xinghai Li, Chao-Chieh Lin, Jen-Tsan Ashley Chi, and Ashutosh Chilkoti. “A paclitaxel-loaded recombinant polypeptide nanoparticle outperforms Abraxane in multiple murine cancer models.” Nat Commun 6 (August 4, 2015): 7939. https://doi.org/10.1038/ncomms8939.

Han, Wei, Sarah R. MacEwan, Ashutosh Chilkoti, and Gabriel P. López. “Bio-inspired synthesis of hybrid silica nanoparticles templated from elastin-like polypeptide micelles.” Nanoscale 7, no. 28 (July 2015): 12038–44. https://doi.org/10.1039/c5nr01407g.

Mastria, Eric M., Mingnan Chen, Jonathan R. McDaniel, Xinghai Li, Jinho Hyun, Mark W. Dewhirst, and Ashutosh Chilkoti. “Doxorubicin-conjugated polypeptide nanoparticles inhibit metastasis in two murine models of carcinoma.” J Control Release 208 (June 28, 2015): 52–58. https://doi.org/10.1016/j.jconrel.2015.01.033.

Ghoorchian, A., J. R. Simon, B. Bharti, W. Han, X. Zhao, A. Chilkoti, and G. P. Lõpez. “Bioinspired reversibly cross-linked hydrogels comprising polypeptide micelles exhibit enhanced mechanical properties.” Advanced Functional Materials 25, no. 21 (June 1, 2015): 3122–30. https://doi.org/10.1002/adfm.201500699.

Kimmerling, K. A., B. D. Furman, D. S. Mangiapani, M. A. Moverman, S. M. Sinclair, J. L. Huebner, A. Chilkoti, et al. “Sustained intra-articular delivery of IL-1RA from a thermally-responsive elastin-like polypeptide as a therapy for post-traumatic arthritis.” Eur Cell Mater 29 (January 31, 2015): 124–39. https://doi.org/10.22203/ecm.v029a10.

Hassouneh, Wafa, Ekaterina B. Zhulina, Ashutosh Chilkoti, and Michael Rubinstein. “Elastin-like Polypeptide Diblock Copolymers Self-Assemble into Weak Micelles.” Macromolecules, 2015. https://doi.org/10.1021/acs.macromol.5b00431.

Liu, Jinyao, Wenge Liu, Isaac Weitzhandler, Jayanta Bhattacharyya, Xinghai Li, Jing Wang, Yizhi Qi, Somnath Bhattacharjee, and Ashutosh Chilkoti. “Ring-opening polymerization of prodrugs: a versatile approach to prepare well-defined drug-loaded nanoparticles.” Angewandte Chemie (International Ed. in English) 54, no. 3 (January 2015): 1002–6. https://doi.org/10.1002/anie.201409293.

Bellucci, Joseph J., Jayanta Bhattacharyya, and Ashutosh Chilkoti. “A noncanonical function of sortase enables site-specific conjugation of small molecules to lysine residues in proteins.” Angewandte Chemie (International Ed. in English) 54, no. 2 (January 2015): 441–45. https://doi.org/10.1002/anie.201408126.

2014

McDaniel, Jonathan R., Isaac Weitzhandler, Sylvain Prevost, Kevin B. Vargo, Marie-Sousai Appavou, Daniel A. Hammer, Michael Gradzielski, and Ashutosh Chilkoti. “Noncanonical self-assembly of highly asymmetric genetically encoded polypeptide amphiphiles into cylindrical micelles.” Nano Letters 14, no. 11 (November 2014): 6590–98. https://doi.org/10.1021/nl503221p.

Li, Nan K., Felipe García Quiroz, Carol K. Hall, Ashutosh Chilkoti, and Yaroslava G. Yingling. “Molecular description of the LCST behavior of an elastin-like polypeptide.” Biomacromolecules 15, no. 10 (October 2014): 3522–30. https://doi.org/10.1021/bm500658w.

Hill, Ryan T., Klaudia M. Kozek, Angus Hucknall, David R. Smith, and Ashutosh Chilkoti. “Nanoparticle-Film Plasmon Ruler Interrogated with Transmission Visible Spectroscopy.” ACS Photonics 1, no. 10 (October 2014): 974–84. https://doi.org/10.1021/ph500190q.

Bhattacharyya, Jayanta, and Ashutosh Chilkoti. “Abstract 4481: Genetically encoded chimeric polypeptide nanoparticles for gemcitabine delivery to solid tumors.” In Cancer Research, 74:4481–4481. American Association for Cancer Research (AACR), 2014. https://doi.org/10.1158/1538-7445.am2014-4481.

Liu, Wenge, Ratul Mukerji, Xinghai Li, Jeff Schaal, Jayanta Bhattacharyya, Michael Zalutsky, and Ashutosh Chilkoti. “Abstract 4583: In situ photocontrolled intratumoral depot for combined photodynamic therapy and brachytherapy for solid tumor.” In Cancer Research, 74:4583–4583. American Association for Cancer Research (AACR), 2014. https://doi.org/10.1158/1538-7445.am2014-4583.

Yousefpour, Parisa, and Ashutosh Chilkoti. “Co-opting biology to deliver drugs.” Biotechnology and Bioengineering 111, no. 9 (September 2014): 1699–1716. https://doi.org/10.1002/bit.25307.

MacEwan, Sarah R., and Ashutosh Chilkoti. “Applications of elastin-like polypeptides in drug delivery.” Journal of Controlled Release : Official Journal of the Controlled Release Society 190 (September 2014): 314–30. https://doi.org/10.1016/j.jconrel.2014.06.028.

Chilkoti, Ashutosh. “Surface initiated polymerization and its applications in medicine.” In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 248. AMER CHEMICAL SOC, 2014.

Ghoorchian, Ali, Ashutosh Chilkoti, and Gabriel P. López. “Simple assay for proteases based on aggregation of stimulus-responsive polypeptides.” Analytical Chemistry 86, no. 12 (June 2014): 6103–10. https://doi.org/10.1021/ac5012574.

MacEwan, Sarah R., Wafa Hassouneh, and Ashutosh Chilkoti. “Non-chromatographic purification of recombinant elastin-like polypeptides and their fusions with peptides and proteins from Escherichia coli.” Journal of Visualized Experiments : JoVE, no. 88 (June 2014). https://doi.org/10.3791/51583.

McDaniel, Jonathan R., Sarah R. MacEwan, Xinghai Li, D Christopher Radford, Chelsea D. Landon, Mark Dewhirst, and Ashutosh Chilkoti. “Rational design of "heat seeking" drug loaded polypeptide nanoparticles that thermally target solid tumors.” Nano Lett 14, no. 5 (May 14, 2014): 2890–95. https://doi.org/10.1021/nl5009376.

Tang, Lei, Vinalia Tjong, Nan Li, Yaroslava G. Yingling, Ashutosh Chilkoti, and Stefan Zauscher. “Enzymatic polymerization of high molecular weight DNA amphiphiles that self-assemble into star-like micelles.” Advanced Materials (Deerfield Beach, Fla.) 26, no. 19 (May 2014): 3050–54. https://doi.org/10.1002/adma.201306049.

Chilkoti, Ashutosh. “Genetically encoded polypeptide nanoparticles for delivery of drugs.” In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 247. AMER CHEMICAL SOC, 2014.